3640例育龄产妇TORCH筛查回顾性分析

Retrospective analysis of TORCH screening among 3 640 women of childbearing age

目的对育龄妇女产前TORCH筛查,并对结果进行回顾性分析。方法采用ELISA法,对2009年1月至2011年5月在暨南大学附属第一医院做产前筛查的3640名育龄妇女进行孕妇致畸八项(TORCH-IgM及IgG抗体)或优生四项(TORCH-IgM抗体)的检测。结果孕妇致畸八项中TORCH-IgM阳性率为2.29%,优生四项中TORCH-IgM阳性率为1.59%,TORCH-IgM总阳性率为2.03%。孕妇致畸八项中Tox-IgG、RV-IgG、CMV-IgG及HSV-II-IgG分别为3.49%、69.60%、83.30%和71.00%。结论广州地区育龄妇女TORCH-IgG阳性率较低,而相应的IgM水平也较文献报道低,表明产妇TORCH既往感染和当前感染率均较低,可能与当前卫生条件的改善有关。

Objective To analyze the TORCH screening results retrospectively of women at childbearing age in Guangzhou city, which can help us to know the epidemiological features of TORCH infection and provide basis for the prevention in the prenatal and postnatal stage. Methods Using indirect enzyme linked immunosorbent assay （ELISA）, 3 640 women at childbearing age were performed prenatal screening test of ‘TORCH-IgM and IgG antibodies’ or ‘TORCH-IgM antibodies’ at the First Affilated Hospital of Jinan University from January 2009 to May 2011. Results The TORCH-IgM positive rate is 2.29% in ‘TORCH-IgM and IgG antibodies’ test, while the positive rate of TORCH-IgM in ‘TORCH-IgM antibody’ test is 1.59%. Totally, the TORCH-IgM positive rate is 2.03%. In ‘TORCH-IgM and IgG antibody’ test, the positive rate of Tox-IgG is 3.49%, RV-IgG is 69.6%, CMV-IgG is 83.3% and HSV-II-IgG is 71.0%. Conclusion Retrospective analysis showed that positive rates of TORCH-IgM and TORCH-IgG in women of childbearing age in Guangzhou city are relatively lower than the rates reported elsewhere previously. The reason may be due to the hygienic improvement in recent years.