α,ω-二元羧酸单酯在铑系双组份催化剂上加氢制ω-羟基羧酸酯

Preparation of ω-Hydroxy Carboxylic Esters from Hydrogenation of α,ω-Dicarboxylic Acid Monoesters over Rh Based Bicomponent Catalysts

在小型高压反应釜中研究了铑系催化剂对于α，ω－ 二元羧酸单酯加氢生成ω－ 羟基羧酸酯的催化性能。结果表明，Ｒｈ － Ｒｅ 以及Ｒｈ － Ｍｏ 双组份催化剂具有良好的催化加氢性能；α，ω－ 十五烷二酸单甲酯在Ｒｈ － Ｒｅ 和Ｒｈ － Ｍｏ双组份催化剂上加氢生成ω－ 羟基十五烷酸甲酯的收率分别达到８７－５ ％ 和８４－７ ％ ；其它α，ω－ 二元羧酸单酯在Ｒｈ －Ｍｏ 双组份催化剂上加氢生成相应的ω－ 羟基羧酸酯的收率也达到８０－９ ％ ～９１－３ ％ 。反应温度对α，ω－ 二元羧酸单酯加氢生成ω－ 羟基羧酸酯的收率有较大的影响，乙二醇二甲醚作为溶剂有利于目的产物的生成。

The catalytic performance of rhodium based bicomponent catalysts in the hydrogenation of α,ω-dicarboxylic acid monoesters to ω-hydroxy carboxylic acid esters was investigated by using a portable autoclave.Rh-Re and Rh-Mo bicomponent catalysts exhibit good activity in the formation of ω-hydroxy carboxylic acid esters,For the hydrogenation of α,ω-pentadecanedionic acid monomethyl ester,the yield of ω-hydroxy pentadecanoic acid methyl ester was 87.5% and 84.7% respectively over Rh-Re and Rh-Mo bicomponent catalysts.The yield of ω-hydroxy carboxylic acid methyl esters reached 80.9%～91.3% in the hydrogenation of other α,ω-dicarboxylic acid monomethyl esters over Rh-Mo bicomponent catalysts.The effect of solvents was also studied,The reaction temperature affects greatly the yield of ω-hydroxy carboxylic acid esters