呼吸支持治疗COPD并发肺性脑病的临床观察和分析

Clinical observation and analysis of respiratory support treat for chronic obstructive pulmonary disease which complicated with pulmonary encephalopathy

目的探讨呼吸(有创呼吸机)支持治疗COPD并发肺性脑病临床治疗效果。方法回顾分析2007年12月至2012年1月我院呼吸内科治疗228例COPD并发肺性脑病按是否给予呼吸支持(有创呼吸机)治疗分为治疗组和非治疗组,分析比较两组的住院天数、治愈率以及死亡率。并对效果采用统计学分析。结果按GOS标准;治疗组经过呼吸支持治疗和抗生素、糖皮质激素、氨茶碱、沙丁胺醇等治疗COPD并发肺性脑病后的住院天数是(10.26±0.66)d明显少于非治疗组(21.12±1.40)d(P<0.05);治愈率:治疗组为89.71%明显高于非治疗组治愈率13.20%(P<0.05);死亡率:治疗组为5.71%明显少于非治疗组死亡率84.90%(P<0.05)。结论及时有效的呼吸支持(有创呼吸机)治疗和抗生素、糖皮质激素、氨茶碱、沙丁胺醇等治疗COPD并发肺性脑病,可有效地控制病情,提高治愈率,降低住院天数和降低死亡率。

Objective To investigate the treatment effectiveness of respiratory support（invasive mechanical ventilation） use in chronic obstructive pulmonary disease（COPD） which complicated with pulmonary encephalopathy.Methods 228 cases of COPD which complicated with pulmonary encephalopathy were divied into treatment group and control group.Compared and analyzed the hospital day,recovery rate and mortality between the two groups.Results The hospital day of treatment group（10.26±0.66）d was significantly lower than the control group（21.12±1.40）d（P0.05）.mortality of treatment group（5.71%） was significantly lower than control group（84.90%）（P0.05）.The recovery rate of treatment group（89.71%） was significantly higher than control group（13.20%）（P0.05）.Conclusion Respiratory support can make the treatment of COPD which complicated with pulmonary encephalopathy more effectiveness.