期刊文献+

艾滋病相关口腔上颚卡波西肉瘤临床特点分析 被引量:5

Related AIDS oral maxillary kaposi sarcoma clinical characteristics analysis
下载PDF
导出
摘要 目的总结两例AIDS相关的口腔上颚卡波西肉瘤(KS)临床诊断治疗经验,了解KS与AIDS的关系,有助于早期诊断和治疗。方法根据病变特点,通过病理组织切片,免疫组化染色以及特殊检查明确诊断口腔上颚KS,对其临床表现,肿瘤特征,治疗方式,疗效进行总结分析。结果两例病例经放疗,抗病毒治疗以及HAART治疗后皮损及口腔病变逐渐好转。结论 KS主要在男性同性恋者中流行,随着HIV通过性传播途径感染的病例不断增加,不排除中原地区发病率增加的可能性,放射治疗对KS是一种安全有效的方法,剂量以40 GY左右为宜,同时给以抗病毒治疗以及HAART治疗,HAART治疗的开始时间与疾病展密切相关。 Objective To summary two cases oral maxillary KS of AIDS related clinical diagnosis and treatment experience,the understanding KS with AIDS relations,conduce to early diagnosis and treatment.Methods According to the lesions characteristic,through the histopathological slice and immunohistochemical stains and special inspection diagnosis,the oral maxillary KS clinical manifestation,tumor characteristics,treatments,efficacy analysis.Results Two cases after radiotherapy,antiviral treatment and of HAART Skin lesions and oral lesions gradually improving.Conclusion KS mainly in male homosexuals in pop,with HIV infection through sexual transmission way of cases increases unceasingly,does not exclude the possibility of China central plains area increased incidence of KS,radiation therapy is a safe and effective method 40 GY doses to around advisable,meanwhile give antiviral treatment and HAART treatment,HAART treatment start time and closely related to disease progression.
出处 《中国实用医药》 2012年第4期24-25,共2页 China Practical Medicine
关键词 卡波西肉瘤 艾滋病 治疗 Kaposi sarcoma AIDS Treatment
  • 相关文献

参考文献5

二级参考文献21

  • 1郜桂菊,张福杰,姚均,赵红心,卢联合,李鑫.HIV感染者/AIDS患者CD_4^+细胞计数与机会性感染对应关系的临床分析[J].中国艾滋病性病,2005,11(4):241-243. 被引量:87
  • 2US.Public Health Service(USPHS)and Infectious Disease Society of America(IDSA).2001 USPHA/IDSA guidelines for the prevention ofopportunistic infected with human Immunodcficiency virus.MMWR.2001.1-68.
  • 3Crowe SM,Carlin JB,Stewart KL,et al.Predictive value of CD lymphocyte numbers for the development of opportunistic infectionsand malignancies in HIV-infected persons.J Acquir Immune Defic Syndr,1991,4:770-776.
  • 4Duvic M, Friedman-Kien AE, Looney DJ, et al. Topical treatment of cutaneous lesions of acquired immunodeficiency syndrome-related Kaposi sarcoma using alitretinoin gel: results of phase 1 and 2 trials.Arch Dermatol, 2000, 136:1461 - 1469.
  • 5Gill PS, McLaughlin T, Espina BM, et al. Phase I study of human chorionic gonadotropin given subcutaneously to patients with acquired immunodeficiency syndrome-related mucocutaneous Kaposi's sarcoma.J Natl Cancer Inst, 1997, 89:1797 - 1802.
  • 6Dezube BJ, Von Roenn JH, Holen-Wiltse J,et al. Fumagillin analog in the treatment of Kaposi's sarcoma: a phase I AIDS Clinical Trial Group study. AIDS Clinical Trial Group No. 215 Team. J Clin Oncol, 1998, I: 1444 - 1449.
  • 7Dupont C, Vasseur E, Beauchet A, et al. Long-term efficacy on Kaposi's sarcoma of highly active antiretroviral therapy in a cohort of HIV-positive patients. CISIH 92. Centre d'information et de soins de l′immunodeficience humaine. AIDS, 2000, 14:987 - 99
  • 8Northfelt DW, Dezube B J, Thommes JA, et al. Pegylated-liposomal doxorubicin versus doxorubicin, bleomycin, and vincristine in the treatment of AIDS-related Kaposi's sarcoma: results of a randomized phase Ⅲ clinical trial. J Clin Oncol, 1998, 16:2445 - 2
  • 9Miles SA, Dezube BJ, Lee JY, et al. Antitumor activity of oral 9 -cis-retinoic acid in HIV-associated Kaposi's sarcoma. AIDS, 2002,16:421 -429.
  • 10Lebbe C, Blum L, Pellet C, et al. Clinical and biological impact of antiretroviral therapy with protease inhibitors on HIV-related Kaposi's sarcoma. AIDS, 1998, 12:F45-49.

共引文献31

同被引文献62

引证文献5

二级引证文献21

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部