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聚桂醇体外杀伤人脐静脉内皮细胞的实验研究 被引量：2

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摘要 目的探讨聚桂醇对体外人脐静脉内皮细胞的杀伤作用。方法体外培养人脐静脉内皮细胞融合细胞株EA.hy926,采用CCK8检测不同浓度的聚桂醇对EA.hy926细胞株的杀伤率。结果不同浓度的聚桂醇对EA.hy926细胞均具有显著杀伤作用,且药物浓度与细胞杀伤率呈正相关。其杀伤率为50%及90%时的药物浓度分别为32μg/ml和521μg/ml。结论聚桂醇注射液对EA.hy926细胞具有明显杀伤作用且药物浓度与细胞杀伤率呈正相关。
作者 刘青 李昭辉 巴亚斯 杨东海 黄小进 徐益鸣 洪诗钗
机构地区 厦门大学附属中山医院血管外科 厦门大学附属中山医院中心实验室
出处 《广西医学》 CAS 2012年第2期226-227,共2页 Guangxi Medical Journal
关键词 聚桂醇 EA.hy926细胞株 杀伤效果 人脐静脉内皮细胞
分类号 R543.6 [医药卫生—心血管疾病] R551.1 [医药卫生—血液循环系统疾病]
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共引文献94

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广西医学
2012年 第2期

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