窄带内镜、染色内镜与常规内镜对远端大肠ACF发现率的对比研究

Detection of aberrant crypt foci in the distal colorectum by colonoscopy:a randomized controlled comparison of conventional imaging,narrow band imaging and chromoendoscopy

目的比较常规内镜与窄带内镜(NBI)、染色内镜对远端大肠异常隐窝灶(aberrant cryptfoci,ACF)的发现率。方法选择2011年8月至12月就诊于江西省萍乡市人民医院准备接受结肠镜检查的患者670例,用随机数字表法将患者分为3组:其中常规内镜组228例、NBI组220例、染色内镜组222例。比较三种方法对远端大肠ACF检出率及各组间所用操作时间。结果在三组中,共发现155例ACF病例数。常规内镜、NBI组及染色内镜组发现ACF病例数分别为5例(2.19%)、25例(11.36%),125例(56.31%),三组组间比较有显著性统计学差异(P<0.01)。但是与常规内镜相比,NBI组、染色内镜组操作时间有所延长。结论染色内镜能大幅提高远端大肠ACF发现率。NBI内镜较常规白光内镜能提高远端结肠ACF发现率,但比染色内镜低。常规白光内镜对远端结肠ACF发现率低。

Aim To compare the detection power of aberrant crypt foci（ACF） by conventional imaging, narrow band imaging, and chromoendoscopy during colonoscopy. Methods Six hundred and seventy outpatients undergoing routine colonoscopy were randomly allocated into three groups conventional imaging, chromoendoscopy, and narrow band imaging. Detection rate ACF and operation time were compared. Results Total 155 patients with ACF were detected during colonoscopy in 3 groups, the detection rates were 2.19% in conventional imaging group, I1.36% in NBI group, and 56.3% in chromoendoscopy group （P 〈 0.01）. The op- eration time was much longer for chromoendoscopy group and NBI group as compared with conventional colonoscopy group. Conclusion Chromoendoscopy and narrow band imaging can improve the detection rate of ACF lesions in the distal colorectum.