自体真皮移植的初步实验观察

AN EXPERIMENTAL STUDY ON CARTILAGINOUS AND PERICHONDRIAL AUTOGRAFT

本文以豚鼠为主要模型,对单层和多层自体真皮移植后体积和皮肤附属器等方面的变化进行观察,并对所出现的某些现象作了讨论。实验结果表明;1.移植后3个月和6个月的真皮都有不同程度的吸收,体积缩小30±～50±％。2.多层真皮重叠移植后吸收较单层严重。3.移植3个月和6个月的真皮中33.3％有囊肿形成,囊内容为皮脂和毛。

Thirty two pieces of ear cartilage, 12 pieces of rib cartilage from 18 adult rabbits were implanted subcutaneously, intramuscularly. It was noticed after 6 months that most of the grafts were unchanged in size, except one piece of ear cartilage being absorbed to a great extent postoperatively. Proliferation of chondrocytes, focal calification and ossification and degeneration of nuclei could be seen in some grafts under microscope, These changes were not related to positions of implantation.Twenty-four ear cartilage grafts from twelve baby rabbits were transplanted. Grafts in two rabbits increased in size and became thickened. Proliferation of perichond-rium and neochondrocytes appeared in another three, there was no sign of growth in the rest,Perichondium graft is able to form cartilage but not in all cases. Elastic cartilage formed in five out of seventeen rabbits' ear perichondium grafts (that is, 29.4%) in this study.