广东台山HIV携带者 艾滋病患者血培养阳性病原菌种类及药敏分析

Drug sensitivity and positive pathogenic bacteria types of blood culture for HIV carriers and AIDS patients in Taishan of Guangdong province

目的了解2009年1月至2011年10月广东台山人类免疫缺陷病毒(HIV)携带者和艾滋病(AIDS)患者血培养阳性病原菌种类及耐药情况,认真执行血培养的标准化操作。方法血培养用美国BD9050全自动血培养仪、法国生物梅里埃公司血培养双相瓶,鉴定、药敏用法国生物梅里埃公司ATB Expression自动细菌鉴定仪。结果 2009年1月至2011年10月46例血培养阳性的HIV携带者和AIDS患者病原菌种类包括22株革兰阳性球菌、10株革兰阴性杆菌、14株真菌,分别占47.8%、21.7%、30.5%;革兰阳性球菌、革兰阴性杆菌、真菌对抗菌药物基本敏感。结论 HIV携带者血培养阳性病原菌主要是金黄色葡萄球菌,AIDS患者血培养阳性病原菌主要是马尓尼菲青霉菌。

Objective To understand drug sensitivity and positive pathogenic bacteria types of blood culture for HIV carriers and AIDS patients in Taishan of Guangdong province from January 2009 to October 2011,also to carry out standard operation of blood culture.Methods Blood culture was processed by United States BD9050 automated blood culture instrument and French bioMerieux biphasic blood culture bottles.Identification and drug sensitivity were tested by French bioMerieux MUI ATB Expression automatic bacteria identification system.Results From January 2009 to October 2011,in 46 cases of blood culture of positive pathogens in HIV carriers and AIDS patients,22（47.8%） were Gram-positive cocci,10（21.7%）were Gram-negative bacilli,14（30.5%）were fungi.Gram-positive cocci,gram-negative bacteria and fungi were sensitive to antimicrobial drugs.Conclusion Staphylococcus aureus is dominant in positive pathogens of blood culture for HIV carriers.Penicillium marneffei is dominant in positive pathogens of blood culture for AIDS patients.