丙泊酚与氯胺酮用于小儿CT检查的效果比较

Clinical comparison of two anesthetics used in CT examination for children

目的观察丙泊酚和氯胺酮静脉麻醉在小儿CT检查中的应用效果及安全性。方法 120例行CT检查的患者随机分成氯胺酮组(K组)和丙泊酚组(P)组,监测两组患者检查前后血压、心率、血氧饱和度,记录患者的入睡时间、检查持续时间、清醒时间。结果两组患者的血压、心率均有波动,但多数无需特殊处理。P组的入睡时间(1.8±0.7)min、清醒时间(5.6±1.8)min明显短于K组的(2.5±1.6)min和(17.1±4.2)min(P<0.05),K组术中及术后躁动的发生率显著高于P组。结论丙泊酚和氯胺酮均可安全用于小儿CT检查,丙泊酚在入睡时间、清醒时间及减轻躁动方面效果优于氯胺酮。

Objective To observe the effect and safety of propofol and ketaraine used in CT exaraination for children. Methods The 120 children patients were randomly derided into two groups： the propofl group（Group P） and the ketamine group （Group K）. Bp, HR and SpO2 were monitored during CT examination. Sleep latency, duration time of exaraination and sleep duration were recorded. Results There were the changes in Bp, HR and Sp02 in both groups but most of which needed no special handling. Sleep latency （1.8±0.7）rain, sleep duration （5.6±1.8） rain in Group P were shorter than in Group K （2.5±1.6,17.1±4.2）rain （P〈0.05）. The incidence of dysphoria was higher in Group K than in Group P. Conclusion When used in CT examination for children, propofol and ketamine were all safe, but propofol was better than ketaraine in sleep latency, sleep duration and in decreasing the incidence of dysphoria.