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Fli-1的研究进展 被引量:1

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摘要 FLi-1最早由Ben-David等在Friend病毒诱导的红白血病细胞中发现^[1]。作为转录因子,Fli-1能够与多种基因的启动子或增强子结合而发挥调节转录的功能,而且还可以通过蛋白质之间的相互作用来调节转录。正常生理条件下,FLi-1主要在造血干细胞和血管内皮细胞中表达。
作者 李岩 崔久嵬
出处 《山东医药》 CAS 2012年第1期107-109,共3页 Shandong Medical Journal
基金 国家自然科学基金资助项目(30901702) 吉林省青年科研基金项目(20080132) 吉林大学杰出青年科学基金项目(201005001)
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  • 7Asano Y,Stawski L,Hant F,et al.Endothelial Fli1 deficiency im-pairs vascular homeostasis.A role in scleroderma vasculopathy[J].Am J Pathol,2010,176(4):1983-1998.
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  • 10Kostyak JC,Naik UP.Megakaryopoiesis:transcriptional insightsinto megakaryocyte maturation[J].Front Biosci,2007,12(1):2050-2062.

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