江苏省丝虫病流行特点及防治

EPIDEMIOLOGICAL FEATURES AND CONTROL OF FILARIASIS OF JIANGSU PROVINCE

丝虫病在江苏流行至少已有800多年的历史。建国后,经过大面积的普查,全省有71个县、市流行丝虫病,其中有60个县、市流行班氏丝虫病,10个县、市为班氏和马来两种丝虫病混合流行区,1个县为马来丝虫病流行区。据50年代调查估计,全省约有微丝蚴血症者和症状体征者250万人。通过30多年来的防治,对丝虫病低度流行区采用反复查治加重点乡村全民服药,中、高度流行区采用全民间隔食用药盐的防治措施,至1988年全省平均微丝蚴率由1958年的4.58%下降为0.07%,有19个县、市降为0。

Filariasis,endemic in Jiangsu for more than 800 years as recorded in the literature, was very harmful to the people.A large scale survey of 15 484 873 persons was performed in the province in 1958 and 709 145 positive microfilariaemia cases were discovered. Among the 75 counties/cities of the province,71 were endemic with filariasis:37 with a microfilaremia rate below 5%,33 from 5.1 to 20% and 1 county above 20.1%. Bancroftian filariasis was endemic in 60 counties/cities,while m(?)layan filariasis in 1 county and mixed infection in 10 counties/cities. For more than 30 years,three different kinds of control measures were used:(1) repeated examination and treatment plus the treatment of the confirmed cases by DEC 1.0g/1d,2.0g/2d,2.4g/3d,3.0g/3d,4.29g/7d.(2)repeated examination and treatm- ent plus mass therapy of DEC 1.5g/3d.(3)repeated examination and treatment plus mass therapy by administering 0.3% DEC salt,9.0g in 6 months or 13.5g in 9 months. By 1988,the microfilariemia rate of the population (village as an unit) in 71 coun- ties dropped to less than 1%,in which 19 counties to zero.