草木犀流浸液片减轻甲状腺术后肿胀疼痛渗出的疗效评价

Evaluation of the efficacy of melilotus extract to reduce postoperative swelling,pain and exudation after thyroidectomy

目的研究草木犀流浸液片用于甲状腺手术后减轻肿胀、疼痛和渗出的疗效。方法将120例良性甲状腺疾病手术患者随机分为治疗组及对照组。治疗组术前1 d开始服用草木犀流浸液片3片,tid,连续7 d;对照组手术方式与治疗组相同,但不予草木犀流浸液片及其他止痛、抗炎药物。观察2组术后48、72 h和术后6 d切口肿胀和疼痛情况,并予评分量化比较。结果治疗组术后48、72 h和术后6 d的肿胀、疼痛和渗出积分均明显低于对照组(P<O.01)。随服药时间延长,治疗组较对照组积分下降率明显增加。治疗组较对照组提前3 d显著缓解肿胀、疼痛、渗出等症状。全组病例服药期间未见不良反应发生。结论草木犀流浸液片能减轻甲状腺术后肿胀、疼痛和渗出症状,且安全有效。

AIM To study the efficacy of melilotus extract tablet to decrease postoperative swelling, pain and exudation after thyroidectomy. METHODS A total of 120 patients with benign thyroid deseases were randomly separated into 2 groups （treatment group and control group）. Treatment group received melilotus extract for 7 d from one day before operation, and so did control. After the symptoms including swelling, pain and exudation were scored, we compared the scores between 2 groups. RESULTS The symptomatic scores of treatment group were lower than those of control group at 48, 72 h, and the 6th day after operation. As melilotus extract tablet was used, compared with control, the ratio of scores of treatment group decreased. Postoperative swelling, pain and exudation were relieved 3 d earlier in melilotus extract group than in control group. All patients had no obvious adverse drug reactions in the period of drug therapy. CONCLUSION Melilotus extract tablet is effective and safe in the treatment of postoperative swelling, pain and exudation after thyroidectomy.