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人3型副流感病毒疫苗的研究进展 被引量：2

An overview of human parainfluenza virus type 3 vaccine
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摘要 人3型副流感病毒是一种主要感染人类肺部上皮细胞的副黏病毒,可引起肺炎和支气管炎,在婴幼儿和免疫力低下的成人中有较高的发病率。经过多年的研究,对人3型副流感病毒疫苗的研究取得了重要的进展,但还没有有效的抗病毒药物和批准的疫苗上市。目前研究主要集中在减毒活疫苗及亚单位疫苗等,对人3型副流感病毒当前疫苗的研究情况做简要的综述。 Human parainfluenza virus type 3（HPIV3） is a respiratory paramyxovirus that infects lung epithelial cells to cause bronchiolitis and pneumonia,and it is also the cause of high morbidity among infant and the immunocompromised elderly people.Although the HPIV3 vaccine research has made important progress after many years of research,no effective antiviral therapy and licensed vaccines exist for HPIV3.Currently,several vaccine development strategies are being explored including live attenuated vaccines and subunit vaccines,etc.This review presented the current vaccine development of human parainfluenza virus type 3.
作者 闫微 井申荣
机构地区 昆明理工大学生命科学与技术学院
出处 《生命科学》 CSCD 2012年第2期181-184,共4页 Chinese Bulletin of Life Sciences
基金 云南省应用基础研究项目(2007C032M) 国家自然科学基金项目(30872398) 国家高技术研究发展计划("863"计划)(2006AA02A227)
关键词 人3型副流感病毒 疫苗 减毒活疫苗 human parainfluenza virus type 3 vaccine live attenuated vaccines
分类号 R373.13 [医药卫生—病原生物学]
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参考文献19

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二级参考文献9

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共引文献19

同被引文献42

  • 1任桂杰,王志玉.副粘病毒包膜糖蛋白分子生物学研究进展[J].病毒学报,2005,21(1):72-75. 被引量：15
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生命科学
2012年 第2期

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