摘要
58例并殖吸虫病人治疗前后应用双抗体夹心 ELISA 检测血清中特异性循环抗原以考核疗效。先后于治疗后1个月,3个月内和6个月内三次采血检测,循环抗原阴性率分别为24.4%(11/45)、73.7%(28/38)和100%(25/25)。同期以对流免疫电泳法检测持异性抗体阴性率分别为2.0%(1/45)、13.2%(5/38)和48%(12/25)。二者间有非常显著的差异(P<0.01)。表明循环抗原检测具有较好的疗效考核价值。采用本方法检测日本血吸虫病人血清1/34例阳性;华支睾吸虫病人2/15例阳性;姜片吸虫病人15例,脑囊虫病人15例和肺结核病人10例检测均阴性。
An ELISA(double sandwich method) was used for observation of the circulating antigen(CAg)in sera from 58 patients with paragonimiasis pre- and post-treatment. While 1 month,3 months and 6 months after treatment,the negative rate of CAg in the patients'sera was 24.4%、73.5% and 100% respectively.This change was more remarka- ble than that of Ab,which was 2.0%,13.2% and 48.0% respectively.Therefore,the detecting CAg in sera could be used for monitoring the curative effect on paragonimiasis. Several other kinds of diseases were also detected,1/34 patients with Schistosomiasis japonica,2/15 with clonorehiasis,0/15 with fasciolopsiasis and 3/15 cases with Pagu- mogonimus skrjabini were positive.
出处
《中国寄生虫病防治杂志》
CSCD
1990年第2期136-138,共3页
Chinese Journal of Parasitic Disease Control
基金
江苏省自然基金
