农村妇女中人乳头状瘤病毒感染情况调查分析

The investigation and analysis on human papillomavirus infection of rural women

目的对本地区农村妇女中人乳头状瘤病毒感染情况进行调查,对其相关的危险因素进行分析。方法调查人群为本地区的20～54岁农村妇女,其均有性生活史。妇女阴道分泌物的收集方法分为自我取样和医生取样,13种高危型HPV感染情况采用HC2进行检测。检测结果异常的患者进行阴道镜检查及组织病理检查。结果本次共调查632例妇女,HPV自我取样标本收集例数为632例,HPV感染率为13.13%,医生取样标本收集例数为630例,HPV感染率为12.38%。宫颈病变的程度越严重,患者越具有较高的HPV感染率(P<0.05);患者具有较高的受教育水平,则具有较高的HPV感染率(P<0.05);与丈夫性伴侣数为1个的妇女比较,丈夫性伴侣数在1个以上的妇女具有较高的HPV感染率(P<0.05)。结论本地区具有较高的HPV感染率,其数值的高低与年龄没有直接的关系,性行为是其主要的一个危险因素。

Objective To survey on human papillomavirus infection in women of this rural region and analyze its related risk factors. Methods The population was women of 20-54 year-old, and they all had sexual history. The ways of vaginal secretions were self-sampling and physician sampling, 13 high-risk HPV infections were tested with HC2. Patients with abnormal test results were examined by colposcopy or histopathology. Results There were 632 women were investigated. The number of HPV self-sampling specimens was 632 cases, and HPV infection rate was 13.13%; The number of physi- cians collected specimens was 630 cases, and HPV infection rate was 12.38%. The more severe the degree of cervical le- sions, the higher HPV infection rate （P 〈 0.05）; The higher levels of education, the higher HPV infection rate （P 〈 0.05）; Com- pared with the women whose husbands had one sexual partner, women whose husbands with a number of sexual partners bad higher HPV infection rate （P 〈 0.05）. Conclusion The region has a high HPV infection rate, and the level of its value has no direct relationship with age, but the main one risk factor is sex.