代谢综合征危险因子的相关性分析

Clinical characteristics of risk factors of metabolic syndrome

目的分析德州市代谢综合征(MS)危险因子的临床特点。方法对2009年德州市机关人员(20～60岁)医保查体资料进行分析,将被调查对象按年龄分为20～30岁、31～40岁、41～50岁和51～60岁四组,分析其MS危险因子—中心性肥胖(男腰围≥90 cm,女腰围≥80 cm)、高收缩压(≥130 mmHg)或高舒张压(≥85 mmHg)、高血糖(空腹血糖≥5.6 mmol/L)、高甘油三酯(≥1.7 mmol/L)以及高密度脂蛋白胆固醇水平降低(c男<1.03 mmol/L,c女<1.29 mmol/L)在不同年龄组的特点。结果 20～30岁组各个危险因子发生率从高到低排列分别为:中心性肥胖(50%)、高甘油三酯(39%)、高密度脂蛋白胆固醇水平降低(37%)、高舒张压(33%)、高收缩压(22%)、高血糖(6%);31～40岁组各个危险因子发生率从高到低排列分别为:中心性肥胖(57%)、高舒张压(47%)、高甘油三酯(41%)、高密度脂蛋白胆固醇水平降低(32%)、高收缩压(26%)、高血糖(14%);41～50岁组各个危险因子发生率从高到低排列分别为:中心性肥胖(71%)、高舒张压(67%)、高收缩压(66%)、高甘油三酯(54%)、高密度脂蛋白胆固醇水平降低(31%)、高血糖(26%);51～60岁组各个危险因子发生率从高到低排列分别为:高舒张压(68%)、高收缩压(63%)、中心性肥胖(58%)、高甘油三酯(50%)、高密度脂蛋白胆固醇水平降低(30%)、高血糖(27%)。结论中心性肥胖和高甘油三酯是德州市机关人员MS的首发和主要的危险因子,高血压和高血糖是MS的晚发临床表现。

Objective To investigate the clinical characteristics of risk factors of metabolic syndrome（MS）.Methods The data were selected from the documents of annual medical insurance health checks of workers at the authorities in Dezhou in 2009.The subjects were divided into four groups according to their age（20-30y,31-40y,41-50y,and 51-60y）.MS risk factors including central obesity（waist circumference≥90 cm in males,≥80 cm in females）,increased systolic blood pressure（≥130 mmHg） and diastolic blood pressure（≥85 mmHg）,elevated levels of blood glucose and triglyceride（fasting glucose≥5.6 mmol/L,triglyceride≥1.7 mmol/L） and decreased level of high-density lipoprotein cholesterol（1.03 mmol/L in males,1.29 mmol/L in females） were investigated and analyzed among the subjects in different age groups.Results MS risk factors were arranged in order of their prevalence in different age stages as follows：（1）central obesity（50%）,elevated levels of triglyceride（39%）,decreased level of high-density lipoprotein cholesterol（37%）,increased diastolic blood pressure（33%）,increased systolic blood pressure（22%）,elevated levels of blood glucose（6%） in the 20-30y group.（2）central obesity（57%）,increased diastolic blood pressure（47%）,elevated levels of triglyceride（41%）,decreased level of high-density lipoprotein cholesterol（32%）,increased systolic blood pressure（26%）,elevated levels of blood glucose（14%） in the 31-40y group.（3）central obesity（71%）,increased diastolic blood pressure（67%）,increased systolic blood pressure（66%）,elevated levels of triglyceride（54%）,decreased level of high-density lipoprotein cholesterol（31%）,elevated levels of blood glucose（26%） in the 41-50y group.（4）increased diastolic blood pressure（68%）,increased systolic blood pressure（63%）,central obesity（58%）,elevated levels of triglyceride（50%）,decreased level of high-density lipoprotein cholesterol（30%）,elevated levels of blood glucose（27%） in the 51-60y group.Conclusion Central obesity and high level of blood triglyceride are the early onset risk factors of MS,and hypertension and high level of blood glucose are the later symptoms of MS in workers at the authorities in Dezhou.