摘要
在我国黄淮平原的新沂县间日疟流行区,应用咯萘啶1.6g 伍用伯喹120mg4d 分服,治疗236例间日疟现症患者,并与241例用氯喹1.5g、伯喹120mg 4d 分服及228例用氯喹1.5g、伯喹180mg 8d 分服治疗的患者进行比较,结果咯伯4d 疗法治疗后10个月内复发率8.5％(包括无症状原虫复燃病例,下同)氯伯4d 疗法的复发率为12.4％,而氯伯8d 疗法复发率3.5％,较前两种疗法显著为低。用间接荧光抗体(IFA)观察,在治疗10个月后转阴率咯伯四日组76.3％,氯伯四日组为73.9％及氯伯八日组为73.3％,无显著差别。
The authors adopted three therapeutic regimens in treating 705 patients with vivax malaria in an endimic area of Huang-Huai Plain in 1981.The patients were divided into three groups.(Pp)4 group:the total dosage of pyronaridine was 1.6g,0.4g daily forg four days;primaquine 30 mg daily for four days.(Cp)4 group:the total dosage of chloroquine was 1.5g,0.375g daily for four days;primaguine 30mg daily for four days. C_4p_8 group:patients treated with a total dosage of chloroquine 1.5g,0.375g daily for four days;primaquine 22.5mg daily for 8 days with a total dosage of 180mg.Followed up till 300 days,The relapse rate of(Pp)4,(Cp)4,and C_4p_8 group was 8.5%,12.4% and 3.5% respectively.Tested by IFAT,the negative rate of IFA,10 months after trea- tment,was 76.3%,73.9% and 73.3% for(Pp)4,(Cp)4 and C_4p_8 respectively.
出处
《中国寄生虫病防治杂志》
CSCD
1990年第4期267-270,共4页
Chinese Journal of Parasitic Disease Control
