持续扩张后任意皮瓣的活力及回缩的动态观察

Viability and dynamic observation of stretchback of the continuously expanded skin flap in the pig model

目的 观察持续扩张后皮瓣的活力及近期修复效果。方法 用小家猪和恒压灌注仪制作持续扩张动物模型 ,A组动物用 180ml扩张器 ,B组动物用 2 10ml扩张器。完成扩张后 3d制作扩张区皮瓣和正常区任意皮瓣 (对照组 )。结果 A组和B组皮瓣的存活长度比正常任意皮瓣分别增加 92 60 %和 91 96% ,A、B两组差别不明显 (P >0 0 5 )。术后早期扩张后皮瓣有明显回缩 ,术后两个月皮瓣的宽度恢复到正常任意皮瓣水平 (P >0 0 5 )。结论 持续快速扩张后皮瓣的存活能力和修复效果可靠 ,可在临床使用。利用大容量扩张器不能进一步增加皮瓣的存活能力。

Objective To investigate the viabliity of the continuously expanded skin flap and the dynamic change of flap stretchback in the pig model. Methods White piglets and a constant pressure\|infusing pump were employed to establish a continuous tissue expansion model. The animals were divided into two groups. The short rectangular expander of 180ml was used in group A and the long rectangular expander of 210ml was used in group B. Three days after completion of the continuous expansion,normal random and expanded skin flaps were created to assess flap viability and stretchback.Results Flap survival length in group A and B increased by 92.60% and 91.96% respectively versus normal random flap. But there was no significant difference in survival length between group A and B. Obvious flap stretchback was observed in the early stage. Eight weeks after flap operation the flap width of group A and B restored to that of the random skin flaps ( P >0 05).Conclusion Continuously fast\|expanded skin flaps are reliable in viability for soft tissue reconstruction. Larger expanders cannot further enhance the viability of the expanded flap.