平阳霉素局部注射治疗体表肿瘤18例观察

Bleomycin A5 local injection treatment of surface tumors 18 cases observed

目的：研究应用平阳霉素注射治疗体表肿瘤的临床疗效.方法：选择我院2008年12月至2010年12月36例体表肿瘤患者为观察对象,全部入选患者随机分为观察组（平阳霉素）组和对照组（鱼肝油酸钠）两组,各18例,比较两组的疗效及并发症.结果：观察组共18例、对照组共18例均顺利完成预期治疗及效果观察,观察组治疗的总有效率显著高于对照组,两组比较,差异有统计学意义,P〈0.05.观察组发热（＞38.5℃）、厌食、呕吐、色素沉着、局部组织凹陷坏死等并发症均明显低于对照组,两组比较,差异有统计学意义,P〈0.05.结论：平阳霉素局部注射治疗体表肿瘤疗效确切,并发症少,值得临床推广.

Objective：To study the clinical efficacy of injection treatment of surface tumors in Pingyangmycin. Methods：From December 2008 to December 2010,36 eases of patients with surface tumors observed object,all enrolled patients were randomly divided into observation group （PYM） group and control group two （sodium morrhuate） ,the 18 eases,two groups were compared the efficacy and complications. Results：The observation group of 18 patients,a total of 18 cases in the control group the successful completion of the expected treatment effect of the observation group treatment efficiency was significantly higher than the two groups,the difference was statistically significant （P〈0.05）. The observation of fever （〉 38.5℃） ,anorexia,vomiting,pigraentation,local tissue necrosis and other complications of depression were significantly lower than the control group,the two groupa,the difference was statistically significant （P〈0. 05）. Conclusion：Pingyangrnycin injection treatment of surface tumor efficacy is exact and fewer complications, worthy of promotion.