老年性白内障晶状体扫描电镜观察

Scanning electron microscopic study of the Ultrastructure of senile cataract lenses

目的 探讨白内障形成的病因。方法 通过扫描电镜技术 ,对 1 0例老年性白内障和 5例正常人的晶状体皮质纤维表面结构进行了观察和分析。结果 正常晶体状体纤维排列整齐 ,均匀一致 ,纤维间以各种突起相互连接。随着层次的加深 ,纤维变扁平 ,突起明显减少。老年性白内障组晶体皮质纤维表面结构与正常人相比有很大差异 ,明显的变化是纤维排列紊乱 ,纤维溶解、融合。突起的肿胀、变形、脱落、崩溃以及变性球样小体的出现。结论 随年龄增长晶状体可溶性蛋白减少 ,不溶性蛋白增加 ,蛋白由高移低级蛋白变性向液化转变。说明白内障的形成与蛋白变性有关。

Scanning electron microscope was used to study the ultrastructural of cataract lens.Methods 5 normal human lense and 10 senile cataractous lense were collected. Results The fibres of normal lense, array regularly and homogenously, there are synaspes between the fibres. The most obvious changes in senile cataractous lenses, were the irregular array of fibres, the swollen and disforming of syraspes, the appearance of destroged and degenerated partides.Conclusions Ulfrastructural changes in senile cataract were significant.