肺螨症患者血清免疫球蛋白测定

DETECTION OF SERUM IMMUNOGLOBULINS IN PULMONARY ACARIASIS PATIENTS

本文采用免疫单扩散法测定了51份肺螨症患者血清的免疫球蛋白IgG、IgA和IgM含量,并以生物素-亲和素酶联免疫吸附试验(ABC-ELISA)测定了其中16份血清的IgE含量。结果显示患者IgM水平与对照组相近,而IgG(169.77±46.91/ml)、IgA(308.39±91.83U/ml)和IgE(458.90±273.64U/ml)则明显增高。提示螨类吸入肺部后可刺激机体引起体液免疫反应。

The IgG, IgA, IgM levels in sera of 51 patients suffered from pulmonary acariasis and the serum IgE level in 16 of them were determined using single immunodiffussion technique or biotin-avidin enzyme immunosorbent assay (ABC-ELISA). The results showed that the IgM level of the patients was approaching to that of the normals while IgG (169.77±46.91U/ml), IgA (308.39±91.83U/ml) and IgE (458.90±273.64U/ml) levels of the patients increased significantly. This suggests that some components of mites may have stimulated the humoral immunoreactions of the host.