七氟醚对耳鼻喉科全麻患者罗库溴铵肌松效应的影响

Effect of Sevoflurane on Neuromuscular Blockade of Rocuronium of Anaesthesia Patients in Department of Otorhinolaryngology

目的:探讨七氟醚对耳鼻喉科全麻患者罗库溴铵肌松效应影响的方法及效果。方法:随机抽取本院耳鼻喉科近期行全麻手术患者82例,随机分成两组,实验组44例,行七氟醚吸入麻醉;对照组38例,行丙泊酚静脉麻醉。在麻醉平稳后静脉注射罗库溴铵0.6mg/kg,对比两组患者的麻醉效果、各项时间指标和不良发应。结果:两组间相比,实验组患者的麻醉总有效率为95.4%,高于对照组的81.6%(P<0.05);实验组起效时间,完全肌松时间,T2-T4出现时间,TOFr恢复时间均优于对照组(P<0.05);实验组不良发应发生率为9.1%,低于对照组的21.1%(P<0.05)。结论:七氟醚可延长耳鼻喉科全麻患者罗库溴铵的肌松效应,优化手术时间,减少不良反应。

Objective： To discuss the methods and effect of sevoflurane on neuromuscular blockade of rocuronium of anaesthesia patients in the department of otorhinolaryngology.Method： Randomly selected 82 anaesthesia patients treated recently in the department of otorhinolaryngology,who were divided into two groups,44 cases in the experiment group received the inhalation anaesthesia of sevoflurane and 38 cases in the control group received the intravenous anaesthesia of propofol.After the anaesthesia was stable,injected 0.6mg/kg of rocuronium and compared the anaesthesia effect and different time indicators and adverse reactions of patients in two groups.Result： The total effective rate of anaesthesia on patients in the experiment group was 95.4%,higher than that of 81.6% in the control group（P0.05）;the onset time,complete recovery time,the appearance of T2-T4 and the recovery time of TOFr in the experiment group were all better than those in the control group（P0.05）;the incidence of adverse reactions in the experiment group was 9.1%,lower than the one of 21.1% in the control group（P0.05）.Conclusion： Sevoflurane can extend the neuromuscular blockade of rocuronium,optimize the operation time and reduce the adverse reactions on patients in the department of otorhinolaryngology.