皮肤肥大细胞瘤6例病例报道及文献复习

Mastocytoma 6 Case Reports and Review of Literatures

目的了解儿童皮肤肥大细胞瘤的临床特点。方法收集诊治的6例儿童皮肤肥大细胞瘤的临床资料，并复习近年来国内文献报道的资料完整的14例病例，分析疾病的临床表现、治疗及随访情况。结果共20例，男7例，女13例，平均年龄（11．7±8．6）个月，平均病程（9．3---6．7）个月。65％的患者出生时即有皮疹。皮损多为单发，以躯干为主。治疗多采取抗组胺药、糖皮质激素或手术切除。10例患儿随访2~60个月．皮损均有一定程度减退．局部遗留色素沉着或色素减退斑。结论肥大细胞瘤主要发生于婴幼儿，通常2岁以前发病，皮疹多为单发．好发于躯干，预后良好。

Objective To understand the clinical features of pediatric mastocytoma. Methods We reportd 6 patients with mastocytomas and selected 14 other cases which have been reported in recent years ,then analyzed the clinical manifestations, treatments and follow-ups. Results There were 7 males and 13 females among 20 mastocytoma patients. The average age and duration was （11.7±8.6）M, （9.3±6.7）M,respectively. 65% patients presented lesions at birth. Most lesions were frequently located on the trunk,Patients were recommend ed to use antihistamines,topical steroids or surgical excision. 10 patients were followed for 2-60 months, showed complete resolution with local hyperpigmentation or hypopigmentation. Conclusions Most cases of pediatric mastocytoma occur in infants and appear during the first 2 years of life, especially on the trunk. The progno- sis of pediatric mastocytoma ,in general, is good.