摘要
用新生儿脐带血红细胞代替成人红细胞,分别连续培养恶性疟原虫33d和50d。红细胞感染率每3～4d增加8～18倍,最高可达20％以上。与成人红细胞比较;培养48h、72h和96h时的脐带血红细胞感染率均高于成人红细胞(P<0.01)。结果表明脐带血是体外培养疟原虫良好的红细胞来源。
Plasmodium falciparum was cultivated with umbilical cord erythrocytes or with erythrocytes from human adults for 33 days and 50 days respectively. The erythrocyte infection rate increased eightfold to eighteenfold at intervals of three to four days, the highest erythrocyte infection rate being more than 20%. Furthermore, the infection rate of umbilical cord erythrocytes was higher than that of adult erythrocytes at 48, 72 and 96 hours of cultivation, respectively (P<0.01). The results suggested that human umbilical cord blood might be a good source of erythrocytes for in vitro cultivation of malaria parasite.
出处
《中国寄生虫学与寄生虫病杂志》
CAS
CSCD
北大核心
1990年第4期281-283,共3页
Chinese Journal of Parasitology and Parasitic Diseases
关键词
体外培养
恶性疟原虫
脐带
红细胞
Cultivation in vitro, Plasmodium falciparum, umbilical cord, erythrocyte.
