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转化生长因子-β对牙种植体骨结合的影响 被引量：6

Transforming growth factor-β and osteointegration of dental implant
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摘要 转化生长因子(transforming growth factor,TGF)-β是一组具有多种功能的多肽,广泛存在于动物正常组织细胞中。在不同条件下,TGF-β对骨形成及骨吸收有双重调节作用,在种植体周骨形成中发挥重要作用。文中就TGF-β对种植体周骨结合形成的影响作一综述。 Transforming growth factor-β （TGF-β） is a group of polypeptides with multiple functions, widely existing in the cells of normal animal tissues. Under different conditions, TGF-β may regulate both bone formation and bone resorption, and plays an important role in the osteointegration process. In this article, we give a review on the effect of TGF-β on the osteointegration of dental implant.
作者 袁晟 张志宏
机构地区 安徽医科大学附属省立医院口腔医学中心
出处 《医学研究生学报》 CAS 北大核心 2012年第2期212-214,共3页 Journal of Medical Postgraduates
关键词 转化生长因子-Β 种植体 骨结合 Transforming growth factor-β Dental implant Osteointegration
分类号 R782.12 [医药卫生—口腔医学]
  • 相关文献

参考文献24

  • 1张敏,邓哲彤,尹海燕,徐军.Smads信号通路在转化生长因子-β1诱导气道上皮细胞转分化中的作用[J].医学研究生学报,2009,22(1):3-6. 被引量：2
  • 2蔡辉,赵智明,修春英,郭郡浩,赵凌杰.丹参酮ⅡA对溶血磷脂酸致新生大鼠心脏成纤维细胞增殖及分泌转化生长因子β1的影响[J].医学研究生学报,2008,21(2):126-128. 被引量：19
  • 3Summer DR,Turner TM,Urban RM,et al.Locally delivered rh TGF-beta2 enhances bone ingrowth and bone regeneration at local and remote sites of skeletal injury[J].J Orthop Res,2001,19(1):85-94.
  • 4Schmidmaier G,Wildemann B,Ostapowicz D,et al.Long-term effects of local growth factor (IGF-Iand TGF-βl) treatment on fracture healing[J].J Orthop Res,2004,22(3):514-519.
  • 5Simpson AE,Stoddart MJ,Davies CM,et al.TGFβ3 and loading increases osteocyte survival in human cancellous bone cultured ex vivo[J].Cell Biochem Funct,2009,27(1):23-29.
  • 6Bosetti M,Boccafoschi F,Leigheb M,et al.Effect of different growth factors on human osteoblasts activities:A possible application in bone regeneration for tissue engineering[J].Biomol Eng,2007,24(6):613-618.
  • 7Zhang H,Aronow MS,Gronowicz GA.Transforming growth factor-beta 1 (TGF-β1) prevents the age-dependent decrease in bone formation in human osteoblast/implant cultures[J].J Biomed Mater Res,2005,75(1):98-105.
  • 8Kale VP.Differential activation of MAPK signaling pathways by TGF-β1 forms the molecular mechanism behind its dose-dependent bidirectional effects on hematopoiesis[J].Stem Cells Dev,2004,3(1):27-38.
  • 9Kale VP,Vaidya AA.Molecular mechanisms behind the dose-dependent differential activation of MAPK pathways induced by transforming growth factor-β1 in hematopoietic cells[J].Stem Cells Dev,2004,13(5):536-547.
  • 10Takai H,Kanematsu M,Yano K,et al.Transforming growth factor-βstimulates the production of osteoprotegerin/osteoclastogenesis inhibitory factor by bone marrow stromal cells[J].J Bio Chem,1998,273(1):27091-27096.

二级参考文献19

  • 1季国忠,王学浩.转化生长因子β-Smad信号转导通路在肿瘤发生中的作用[J].医学研究生学报,2005,18(6):542-545. 被引量：9
  • 2修春英,蔡辉.溶血磷脂酸与缺血性心脏病[J].医学研究生学报,2006,19(2):172-174. 被引量：3
  • 3张敏,徐军.转化生长因子-β_1体外诱导气道上皮细胞向肌纤维母细胞转分化[J].广东医学,2006,27(5):647-649. 被引量：4
  • 4Beckett PA, Howarth PH. Pharmacotherapy and airway remodelling in asthma? [J] Thorax, 2003,58(2) :163-174.
  • 5Gabbrielli S, Di Lollo S, Stanflin N, et al. Myofibroblast and elastic and collagen fiber hyperplasia in the bronchial mucosa: a possible basis for the progressive irreversibility of airway obstruction in chronic asthma [ J ]. Pathologica, 1994,86 ( 2 ) : 157- 160.
  • 6Ward C, Forrest IA, Murphy DM, et al. Phenotype of airway epithelial cells suggests epithelial to mesenchymal cell transition in clinically stable lung transplant recipients [ J ]. Thorax, 2005,60 (10) :865-871.
  • 7Ogawa E, Elliott WM, Hughes F, et al. Latent adenoviral infection induces the production of growth factors relevant to airway remodeling in COPD [ J]. Am J Physiol Lung Cell Mol Physiol, 2004, 286( 1 ) :L189-197.
  • 8Zimmerman CM, Padgett RW. Transforming growth factor β signaling mediators and regulators [ J ]. Gene, 2000,249 ( 1-2 ) : 17- 30.
  • 9Li JH, Zhu H J, Huang XR. Smad7 inhibits fibrotic effect of. TGF-βon renal tubular epithelial cells by blocking Smad2 activation[J]. J Am Soc Nephrol, 2002,13(6) :1464-1472.
  • 10Sato M, Muragaki Y, Saika S, et al. Targeted disruption of TGF- β1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction [ J ]. J Clin Invest, 2003,112(10) : 1486-1494.

共引文献18

同被引文献88

  • 1张玮,王少安.转化生长因子-β1与种植体骨整合的研究进展[J].国际口腔医学杂志,2008,35(S1):250-252. 被引量：3
  • 2李良勇,李家林,谢成娟,王玉.经鼻给予TGFβ1对癫痫持续状态大鼠海马神经元的保护作用[J].中风与神经疾病杂志,2012,29(2):109-112. 被引量：4
  • 3董常生,贺俊平,高贵民.鸡实验性骨折愈合过程TGF-β1免疫组织化学研究[J].解剖学报,2004,35(5):534-536. 被引量：1
  • 4李守宏,庞光明,陈建钢.TGF-β1复合物诱导颌骨成骨过程中微血管的形成与表达[J].临床口腔医学杂志,2007,23(3):137-139. 被引量：3
  • 5Bomstein MM, Lussi A, Schmid B, et al. Early load- ing of nonsubmerged titanium implants with a sand- blasted and acid-etched (SLA) surface:3-year re- sults of a prospective study in partially edentulous patients [J] .Int J Oral Maxillofac Implants, 2003, 18 (5) :659-666.
  • 6O' Driscoll SW, Fitzsimmons JS. Clin Orthop Relat Res, 2001, (391 Suppl) : S190- 207.
  • 7Lamberg A, Schmidmaler G, Soballe K. Locally de- livered TGFbetal and IGF-1 enhance the fixation of titanium implants: A study in dogs [J] .Acta Or- thop, 2006, 77 (5): 799-805.
  • 8Tielinen L, Puolakkainen P, Pohjonen T.The effect of transforruing growth factorβ1, released from a bioabsorbable self-reinforced polylactide pin, on a bone defect [J] .Biomaterials, 2002, 23 (18) : 3817-3823.
  • 9Vehof JW, Hans MT, de Ruijter AE, et al.Bone formation in Transform ing Growth Factor betal loaded titanium fiber mesh implants [J] .Clin Oral Impl Res, 2002, 13 (1): 94-102.
  • 10Nikolidakis, D, et al. The effect of a low dose of transforming growth factor betal (TGF-beta1) on the early bone-healing around oral implants inserted in trabecular bone. Biomatefials, 2009, 30(1): 94-9.

引证文献6

二级引证文献26

医学研究生学报
2012年 第2期

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