氟化钠甘油过敏1例

Allergy caused by sodium fluoride glycerin: A case report

近年来药物过敏引起的口腔黏膜溃疡越来越多,但氟化钠甘油过敏引起的溃疡却极少见。山东大学千佛山校区医院遇到氟化钠甘油过敏1例,氟化钠甘油治疗后患者口腔黏膜充血水肿明显,颊、腭黏膜有大量红色粟粒状颗粒,3 h后出现吞咽困难,但无呼吸困难,次日出现口腔黏膜大面积溃疡。治疗7 d后患者痊愈,氟化钠敏感试验结果为阳性。

In recent years,though more and more ulcerations of oral mucosa caused by allergy to drug occurred clinically,allergy to sodium fluoride glycerin is extremely rare.A case of allergy to sodium fluoride glycerin occurred in Qianfoshan Campus Hospital of Shandong University.After treatment by sodium fluoride glycerin,there was mucosal edema,a large number of red miliary granules in buccal and palatal mucosa.After 3 hours,there were swallowing difficulties,but no breathing difficulties.Next day large ulcers of oral mucosa developed.The patient was cured 7 days after treatment.Fluoride-sensitive test result was positive.