1Hesson L,Bièche I,Krex D,et al.Frequent epigenetic in-activation of RASSF1Aand BLU genes located within the critical3p21.3region in gliomas[J].Oncogene,2004,23(13):2408-2419.
2Wistuba II,Behrens C,Virmani AK,et al.High resolution chromosome3p allelotyping of human lung Cancer and preneoplastic/preinvasive bronchial epithelium reveals multiple,discontinuous sites of3p allele loss and three re-gions of frequent breakpoints[J].Cancer Res,2000,60(7):1949-1960.
3Wistuba II,Maitra A,Carrasco R,et al.High resolution chromosome3p,8p,9q and22q allelotyping analysis in the pathogenesis of gallbladder carcinoma[J].Br J Cancer,2002,87(4):432-440.
4Maitra A,Wistuba II,Washington C,et al.High-resolu-tion chromosome3p allelotyping of breast carcinomas and precursor lesions demonstrates frequent loss of heterozy-gosity and a discontinuous pattern of allele loss[J].Am J Pathol,2001,159(1):119-130.
5Lerman MI,Minna JD.The630-kb lung Cancer homozygous deletion region on human chromosome3p21.3:identification and evaluation of the resident candidate tumor suppressor genes.The International Lung Cancer Chromosome3p21.3Tumor Suppressor Gene Consortium[J].Cancer Res,2000,60(21):6116-6133.
6Ito M,Ito G,Kondo M,et al.Frequent inactivation of RASSF1A,BLU,and SEMA3Bon3p21.3by promoter hypermethylation and allele loss in non-small cell lung Cancer[J].Cancer Lett,2005,225(1):131-139.
7Ansieau S,Leutz A.The conserved Mynd domain of BS69 binds cellular and oncoviral proteins through a common PXLXP motif[J].J Biol Chem,2002,277(7):4906-4910.
8Manne U,Gary BD,Oelschlager DK,et al.Altered subcel-lular localization of suppressin,a novel inhibitor of cell-cy-cle entry,is an Independent prognostic factor in colorectal adenocarcinomas[J].Clin Cancer Res,2001,7(11):3495-3503.
9Agathanggelou A,Dallol A,Züchbauer-Müller S,et al.Epigenetic inactivation of the candidate3p21.3suppres-sor gene BLU in human cancers[J].Oncogene,2003,22(10):1580-1588.
10Balch C,Yan P,Craft T,et al.Antimitogenic and chemo-sensitizing effects of the methylation inhibitor zebularine in ovarian Cancer[J].Mol Cancer Ther,2005,4(10):1505-1514.
2Jones PA,Takai D.The role of DNA methylation in mammalian epigenetics[J].Science,2001,293(5532):1068-1070.
3Chan MW,Chan LW,Tang NL,et al.Hypermethylation of multiple genes in tumor tissues and voided urine in urinary bladder cancer patients[J].Clin Cancer Res,2002,8(2):464-470.
4Chung WB,Hong SH,Kim JA,et al.Hypermethylation of tumor-related genes in genitourinary cancer cell lines[J].J Korean Med Sci,2001,16(6):756-761.
5Chan MW,Chan LW,Tang NL,et al.Frequent hypermethylation of promoter region of RASSF1A in tumor tissues and voided urine of urinary bladder cancer patients[J].Int J Cancer,2003,104 (5):611-616.
6Lerman MI,Minna JD.The 630-kb lung cancer homozygous deletion region on human chromosome 3p21.3:identification and evaluation of the resident candidate tumor suppressor genes[J].Cancer Res,2000,60(21):6116-6133.
7Agathanggelou A,Dallol A,Zochbauer-Muller S,et al.Epigenetic inactivation of the candidate 3p21.3 suppressor gene BLU in human cancers[J].Oncogene,2003,22(10):1580-1588.
8Balch C,Yan P,Craft T,et al.Antimitogenic and chemosensitizing effects of the methylation inhibitor zebularine in ovarian cancer[J].Mol Cancer Ther,2005,4(13):1505-1514.
