玻璃酸钠关节腔填充踝关节骨折后创伤性关节炎的6个月随访

A 6-month follow-up of hyaluronate sodium intra-articular injection for the treatment of traumatic arthritis after ankle fracture

背景:玻璃酸钠主要用于骨性关节炎的治疗,踝关节骨折术后创伤性关节炎主要也是关节软骨的退变。目的:观察玻璃酸钠踝关节腔内注射治疗踝关节骨折后创伤性关节炎的疗效。方法:选取2009-07/2011-06就诊于承德医学院附属医院康复医学科的踝关节骨折修复后创伤性关节炎患者60例行关节腔内玻璃酸钠注射,分别于治疗后、治疗后1,6个月后对比治疗前后踝关节疼痛、关节活动范围及无痛行走距离等方面改善的差异。结果与结论:60例患者踝关节疼痛目测类比量表评分较治疗前明显降低(P<0.01);关节活动范围与治疗前比较其度数明显增加(背伸、跖屈、内收、外展、内翻与治疗前比较P<0.01,外翻与治疗前比较P<0.05;无痛行走距离比治疗前增加(P<0.01)。结果证实,玻璃酸钠关节腔内注射可以明显改善踝关节创伤性关节炎的临床症状与踝关节功能。

BACKGROUND： Hyaluronate sodium is mainly used for the treatment of osteoarthritis; the traumatic arthritis after ankle fracture is mainly the degeneration of articular cartilage. OBJECTIVE： To observe the therapeutic effect of hyaluronate sodium intra-articular injection on the treatment of traumatic arthritis after ankle fracture. METHODS： Sixty patients with traumatic arthritis after ankle fracture were selected in the Department of Rehabilitation, Affiliated Hospital of Chengde Medical College from July 2009 to June 2011; the patients were treated with hyaluronate sodium intra-articular injection. The ankle pain, range of motion and traveled distance without pain were evaluated at 1 and 6 months after treatment. RESULTS AND CONCLUSION： Compared with pre-treatment, the visual analogue scale was significantly decreased （P〈0.01）; the range of motion was increased, including angles of extensor expansion, plantar flexion, adduction, abduction, enstrophe （P〈0.01）, as well as angles of extroversion （P〈0.05）; traveled distance without pain was increased （P〈0.01）. Hyaluronate sodium intra-articular injection can improve the clinical symptoms of traumatic arthritis after ankle fracture and the ankle function.