胎膜早破亚临床绒毛膜羊膜炎与妊娠结局的关系

Correlation between premature rupture of membranes with subclinical chorioamnionitis and pregnancy outcomes

目的探讨胎膜早破亚临床绒毛膜羊膜炎与妊娠结局的关系。方法回顾性分析192例胎膜早破病例资料。结果胎膜早破亚临床绒毛膜羊膜炎发生率较高,占胎膜早破绒毛膜羊膜炎的76.8%,亚临床绒毛膜羊膜炎组与非绒毛膜羊膜炎组在产褥感染、产后出血、胎盘残留、胎儿窘迫、新生儿感染、病理性黄疸发病率方面差异有统计学意义(P<0.05),而在剖宫产率、低出生体重儿发生率方面差异无统计学意义。结论胎膜早破亚临床绒毛膜羊膜炎与不良妊娠结局密切相关,应重视胎膜早破亚临床型的绒毛膜羊膜炎,加强监测与积极治疗,以减少不良妊娠结局的发生。

OBJECTIVE To investigate the correlation between premature rupture of membranes（PROM） with subclinical chorioamnionitis and pregnancy outcomes.METHODS A total of 192 cases of premature rupture of membranes in our hospital were analyzed retrospectively.RESULTS The incidence of subclinical chorioamnionitis in PROM was high,accounting for 76.8% of chorioamnionitis in PROM.Subclinical chorioamnionitis group and non-chorioamnionitis group had significant differences in puerperal infection,postpartum hemorrhage,fetal distress,residual placenta,neonatal infection and the incidence of pathological jaundice（P0.05）,while there were no significant difference in caesarean section rate and incidence of low birth weight infant.CONCLUSION Premature rupture of membranes with subclinical chorioamnionitis is closely correlated with adverse pregnancy outcomes.We should pay more attention to the subclinical chorioamnionitis,enhance the monitoring and active treatment so as to reduce the incidence of adverse pregnancy outcomes.