220例痰假丝酵母菌属培养阳性患者抗真菌治疗分析

Antifungal treatemt of Candiacultured positive from sputum of 220 patients

目的探讨并分析临床对痰假丝酵母菌属培养阳性患者的治疗情况,为临床医师抗真菌感染治疗提供依据。方法采用回顾性调查方法,对220例痰假丝酵母菌属培养阳性患者抗真菌治疗病例资料进行统计、归纳、分析。结果 220株假丝酵母菌属中,白色假丝酵母菌158株,占71.8%;进行影像检查179例,占81.4%;220例痰假丝酵母菌属培养阳性患者,符合确诊病例仅1例,占0.5%;符合临床诊断病例为2例,占0.9%;疑似病例217例,占98.7%;220例患者中133例进行了预防性抗真菌治疗;科室排序依次为呼吸内科、内科监护病房、肺部肿瘤科。结论综合分析假丝酵母菌属感染患者临床症状、影像学及实验室检测结果,才能进行科学的诊断分级,给予早期积极有效的治疗。

OBJECTIVE To explore and analyze the treatment of the patients who were with sputum culture positive of Candida,so as to provide basis for antifungal treatment.METHODS By the means of retrospective survey,the clinical data of 220 patients whose sputum were cultured positive for Candida were analyzed and susmurized statistically.RESULTS Of 220 strains of Candida,there were 158（71.8%） C.albicans isolates;totally 179（81.4%） cases underwent imaging examination;among the 220 cases of sputum culture Candida positive,only one（0.5%） case was confirmed;there were 2（0.9%） cases who were in line with confirmed cases;there were 217（98.7%） suspected cases;among the 220 patients,totally 133 patients underwent preventive antifungal treatment;the clinical departments were in order as follows：department of respiratory medicine,internal medicine care unit,and department of pulmonary tumors.CONCLUSION To comprehensively analyze the clinical symptoms of tha patients with Candida infections and the results of imaging examination and laboratory test can ensure the scientific classification of diagnosis and effective treatment in early stage.