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DNA甲基化及其与动脉粥样硬化的关系 被引量:3

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摘要 流行病学调查结果表明冠心病有明显的遗传倾向,其发病具有明显的家族聚集性。动脉粥样硬化是导致冠心病的主要因素,DNA甲基化是表观遗传学重要组成部分,调节特异性基因的表达,引起动脉粥样硬化,从而导致冠心病的发生。该文介绍了DNA甲基化及其在动脉粥样硬化的发生、发展方面的相关作用机制。
作者 王丽 赵翠萍
出处 《国际心血管病杂志》 2012年第2期79-82,共4页 International Journal of Cardiovascular Disease
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同被引文献17

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