PCT、CRP在支气管哮喘合并呼吸道感染中的诊断价值

Discusses the PCT,CRP bronchus asthma merger of respiratory tract infection diagnostic value

目的探讨血清降钙索原(PCT)、C反应蛋白(CRP)对哮喘合并感染患者的诊断价值。方法对120例哮喘及哮喘合并感染者采用免疫发光法定量测定患者血清PCT水平,自动免疫散射速率比浊法测定CRP水平。结果哮喘合并细菌感染患者PCT、CRP水平明显高于哮喘合并病毒感染及单纯哮喘患者(P<0.01)。哮喘合并细菌感染组中PCT和PCRP水平明显高于哮喘合并病毒感染组和单纯性哮喘组(P<0.01)。哮喘合并病毒感染组PCT轻度增加,与单纯性哮喘组比较差异虽有统计学意义(P<0.05),但诊断价值不明显。以PCT≥0.5μg/L为界,诊断细菌感染的敏感性87.5%(49/56),以CRP≥10mg/L为界,诊断细菌感染的敏感性为71.1℅。结论血清学PCT、CRP指标能早期正确鉴别哮喘合并细菌感染患者,血清PCT、CRP水平高低可作为是否使用抗菌药物的参考依据。

Objective To explore the serum calcium down the original（PCT）,C-reactive protein（CRP） to asthma amalgamative infection patients diagnostic value.Methods 120 cases of asthma and asthma with infections by immune shine law quantitatively patients serum PCT level,automatic immune scattering rate than turbidity method to determine the CRP level.Results Patients with asthma bacterial infections PCT,CRP level was significantly higher than the asthma merger virus infection and pure asthma patients（P〈0.01）.Asthma bacterial infections in the group with PCT and c-reactive protein（CRP） level was significantly higher than the asthma merger virus infection group and simple asthma group（P〈0.01）.Asthma merger virus infection PCT group a slight increase,and simple asthma group compared though statistically significant difference（P〈0.05）,but the diagnosis value is not obvious.PCT in frequency 0.5 μg/L as a border,diagnosis bacterial infections sensitiity 87.5%（49/56）,with CRP quartile 10 mg/L for world,diagnosis of bacteria infection sensitivity of 71.1℅.Conclusion serological PCT,CRP indicator can correctly identify early bacteria infection patients with asthma,serum PCT,CRP level can be used as whether to use antimicrobial drugs reference.