CO_2肝动脉超声造影对肝癌肝动脉栓塞治疗效果的即时评估

Immediate evaluation on treatment effect of the hepatic artery embolization by CO 2 hepatic artery sonography

目的 探讨肝癌肝动脉栓塞(TAE)治疗疗效即时评估的新方法。方法 对肝癌行TAE患者,即时观察碘油栓塞后肿瘤声像图变化,然后经介入导管注射超声造影剂,动态观察造影剂在瘤内分布以评估肿瘤血管的栓塞程度,并和介入当时X线显示的碘油沉积和彩色多普勒显示的肿瘤血流信号作对照。结果 肝超声造影,5个病灶显示瘤内无造影剂进入,3个病灶显示肿瘤周边局部有少量造影剂进入,1个病灶清晰显示造影剂沿肿瘤血管蜿蜒迂曲进入肿瘤内部,并使瘤内较大范围回声增强。而栓塞治疗当时8例9个病灶在X线下均显示肿瘤内碘油充盈良好;彩色多普勒仅1个病灶内检测到搏动性彩点。应用超声造影评估的TAE栓塞效果和TAE治疗后随访的实际疗效相符合。结论 肝动脉超声造影能在TAE当时评估TAE的远期疗效。

Objective To probe into a new method for immediate evaluation on treatment effect of the hepatic artery embolization(TAE).Methods The changes of ultrasound imaging were observed first right after TAE,then inject CO 2 microbubbles into hepatic artery through the remaining tube and observe the dynamic changes of the imaging due to CO 2 microbubbles perfusion in tumors,and the results were compared with those of oil diposit in tumor showed by X ray and blod persion in tumor showed by color Doppler.Results There is no entry of CO 2 microbubbles in 5 tumors,and a little entry in 3 tumors,and a large number entry in 1 tumor,when CO 2 hepatic artery sonography was performed.These results tally with those of deposit of id oil in CTA,fall of AFP,reduce of tumor size.Conclusions CO 2 HAS can be used for immediate evaluating treatment effect of liver cancer of hepatie artery embolization,and better than those showed by X ray and color Doppler ultrasonography.