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碱性成纤维细胞生长因子对骨组织的生物学效应 被引量：2

The Biological Function of bFGF to Bone Tissue
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摘要 目的 :通过本文的综述 ,使读者了解碱性成纤维细胞生长因子的生物学特性及对骨组织的生物学效应。方法 :采用光盘检索及查询有关中外文献。结果 :碱性成纤维细胞生长因子是一种生物因子 ,其可以诱导骨组织及血管组织细胞的分裂。结论 :碱性成纤维细胞生长因子有诱导成骨作用及诱导血管的形成。 Aim:To understand the biological characterization of the basic fibroblast growth factor (bFGF)and the biological effects to bone tissue.Methods:Using medical document disc rerieval and referring the documents of Chinese and foreign.Results:bFGF is a biological factor,which can induce cellular proliferation of bone tissue and vascular tissue.Conclusion:bFGF has the functions of inducing the bone formation and the vascularization.
作者 沈红雷 吴军正
机构地区 解放军第 第四军医大学口腔医学院口腔生物学教研室
出处 《中国矫形外科杂志》 CAS CSCD 2000年第2期181-183,共3页 Orthopedic Journal of China
关键词 检索 成骨作用 BFGF 生物学效应 Basic fibroboast growth factor Rerieval Bone formation
分类号 R336 [医药卫生—人体生理学]
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参考文献9

  • 1Jaye M, Schlessinger J, Craig A, et al.FGFRtyrosine kinases moolecular analysis and signal transduction[J]. Biochem BiochemActa,1992,1 135:185.
  • 2Brighton CT. Principles of fracture healing . In: cornell CN,Lane JM. Newestfactors in fracture healing[J]. Clin Orthop,1992,277:297.
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同被引文献34

  • 1徐荣辉,饶寒敏,朱雅萍,柴本甫.皮肤成纤维细胞在体外培养中的成骨作用[J].中华外科杂志,1994,32(3):190-192. 被引量：10
  • 2Cospodarowicz D.Purification of a fibroblast growth factor from bovine piyuitary[J].Biol Chem,1975,250(20):2515
  • 3Wang JS,Aspenberg P.Basic fibroblast growth factor and bone induction in rats[J].Acta Orthop Scand,1993,64 (7):557
  • 4Okada Banm,Thiery JP,Jouanneau J.fibroblast growth factor 2[J].Int J Biochem,2000,32 (3):263
  • 5Nakajima A,Nakajima F,Shimizu S,et al.Spatial and temporal gene expression for fibroblast growth factor type Ⅰ receptor (FGFR1) during fracture healing in the rat[J].Bone,2001,29(5):458
  • 6Jaye M,Schlessinger J,Craig A,et al.FGFR tyrosine kinase smoolecular analysis and signal transduction[J].Biochem Biochem Acta,1992,1135 (1):185
  • 7Brighton CT.Principles of fracture healing.In:cornell CN,LaneJM.Newest factors in fracture healing[J].Clin orthop,1992,277:297
  • 8Montesano R,Vassalli JD,Baird A,et al.Basic fibrobast growth factor induces angiogenesis in vitro[J].Proc Natl Acad Sci (USA),1996,83(20):7297
  • 9Globus R,Plouet J,Gospodarowicz D.Cultured bovine bone cellssynthesine fibroblast growth factor and store it in their extracellular matrix[J].Endocrinology,1989,124 (10):1539
  • 10Moursi AM,Winnard PL,Winnard AV,et al.Fibroblast growth factor 2 induces increased calvarial osteoblast ploliferation and craninal suture fusion[J].Cleft Palate Craniofae J,2002,39(6):487

引证文献2

二级引证文献3

中国矫形外科杂志
2000年 第2期

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