流行性喘憋性肺炎流行特征初探

Analysis of epidemic characterisics of epidemic asthmatic pneumonia

目的 通过对浙江省流行性喘憋性肺炎进行长期监测 ,剖析其在我国首次流行的特征、病原、临床表现及控制。方法 用流行病学观察法进行监测。实验用人胚肾细胞培养方法分离病毒。结果 1971～ 1997年共登记报告 15 1935例 ,死亡 6 6 9例。 1971年发病 1316 15例 ,死亡 5 2 4例。流行多发生于夏秋季 ,以农村、山区为重。 3岁组发病率高达 15 337/ 10万。病人起病急 ,有发热、咳嗽和喘憋等症状。用人胚肾细胞培养方法 ,从 41份标本中分离、鉴定 14株呼吸道合胞病毒(RSV )。结论 流行性喘憋性肺炎由 RSV引起。

Objective To analyse epidemic characteristics, pathogen, clinical manifestation and control of pandemic EAP in China through long surveillance in Zhejiang. Methods Epidemiological observation and experiment of isolating virus through culture of human embryo kidney cell were used in this study. Results 151 935 cases were reported during 1971～1997, among whom 669 cases died. In 1971, 131 615 people fell ill, and 524 cases died. Epidemic seasons were autumn and summer. Most cases occurred in rural areas, particularly in mountain areas. Incidence rate of 3 year old group was up to 15 337/100 000. Main clinical symptoms were fever, cough and asthma and so on. 14 strains of RSV were separated and identified from 41 samples through culture of human embryo kidney cell. Conclusions RSV is pathogen of EAP.