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奥卡西平致低钠性昏迷二例 被引量：3

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摘要 例1男性，78岁，75kg，因“发作性左侧肢体抽搐伴意识不清3年，再发2h”于2010年11月7日入院。既往有冠心病10年、右侧颞叶脑梗死病史5年。3年前发作性左侧肢体抽搐伴意识不清5次，每次1～2min，口服卡马西平未发作1年后自行停药。入院前2h类似发作6次，体检：心脏浊音界左下扩大，神经系统检查无明显异常。脑电图示右侧导联为主的慢波增多，头颅MRI示右侧颞叶软化灶，血生化检测正常。
作者 王根娣 钟建国 罗容
机构地区 江苏省盐城市东南大学医学院附属盐城医院神经内科
出处 《中华神经科杂志》 CAS CSCD 北大核心 2012年第3期162-162,共1页 Chinese Journal of Neurology
关键词 低钠性昏迷 奥卡西平 复杂部分性发作 神经系统检查 意识不清 肢体抽搐 心脏浊音界 头颅MRI
分类号 R742.1 [医药卫生—神经病学与精神病学]
  • 相关文献

参考文献3

  • 1抗癫痫药物应用专家共识[J].中华神经科杂志,2011,44(1):56-65. 被引量：184
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  • 3Lin CH, Lu CH, Wang FJ, et al. Risk factors of oxcarbazepine- induced hyponatremia in patients with epilepsy. Clin Neuropharmacol, 2010, 33: 293-296.

二级参考文献20

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共引文献183

同被引文献23

  • 1高乐虹,孟祥红,刘刚,孙伟.奥卡西平对癫痫患者血钠的影响因素分析[J].中华临床医师杂志（电子版）,2011,5(20):6170-6171. 被引量：7
  • 2张丽,周权.奥卡西平致严重药疹反应1例[J].天津药学,2007,19(5):34-34. 被引量：3
  • 3Gumbrevicius G, Sveikata A. A case of severe hyponatremia in a patient suffering from epilepsy and using oxcarbazepine. Medicina (Kaunas), 2006, 42:649-652.
  • 4Lin CH, Lu CH, Wang FJ, Tsai MH, Chang WN, Tsai NW, Lai SL, Tseng YL, Chuang YC. Risk factors of oxcarbazepine-induced hyponatremia in patients with epilepsy. Clin Neuropharmacol, 2010, 33:293-296.
  • 5Ortenzi A, Paggi A, Foschi N, Sahbatini D, Pistoli E. Oxcarbazepine and adverse events: impact of age, dosage, metabolite serum concentrations and concomitant antiepileptic therapy. Funct Neurol, 2008, 23:97-100.
  • 6Letmaier M, Painold A, Holl AK, Vergin H, Engel R, Konstantinidis A, Kasper S, Grohmann R. Hyponatraemia duringpsychopharmacological treatment: results of a drug surveillance programme. Int J Neuropsychopharmacol, 2012, 15:739-748.
  • 7Tebb Z, Tobias JD. New anticonvulsants: new adverse effects. South Med J, 2006, 99:375-379.
  • 8Gumbrevicius G, Sveilkata A. A case of severe hy- ponatremia in a patient suffering from epilepsy and using oxcarbazepine[ J]. Medicina ( Kaunas ), 2006,42 ( 8 ) : 649-652.
  • 9LinC H, LuC H, Wang F J, et al. Risk factors ofox- carbazepine-induced hyponatremia in patients with epilep- sy [ J ]. Clin Neuropharmacol, 2010,33 ( 6 ) :293 -296.
  • 10Ortenzi A, Paggi A, Foschi N, et al. Oxcarbazepine and adverse events: inpact of age, dosage, metabolite serum concentrations and concomitant antiepileptic therapy[ J]. Funct Neurol, 2008,23 (2) :97-100.

引证文献3

二级引证文献16

中华神经科杂志
2012年 第3期

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