遗传性出血性毛细血管扩张症临床特点及基因研究
被引量:3
摘要
遗传性出血性毛细血管扩张症(hereditaryhaemorrhagictelangiectasia,HHT)最常见的症状是反复发生的鼻出血,且鼻出血常常难以控制和治疗,更难根治,严重者可导致贫血和休克,甚至危及生命。HHT是常染色体显性遗传病,目前已经克隆出2个基因,分别位于9号和12号染色体;新近又定位了2个基因,分别位于5号和7号染色体,能否从基因方面治疗该病成为许多学者研究的目标。本文对HHT临床特点及其基因研究进展做一综述。
出处
《国际耳鼻咽喉头颈外科杂志》
2012年第2期102-106,共5页
International Journal of Otolaryngology-Head and Neck Surgery
基金
基金项目:全军十一五科技攻关课题资助项目(08G118)
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