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氨溴索佐治新生儿胎粪吸入综合征的疗效及对血中N0、ET-1的影响 被引量:4

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摘要 [目的]探讨氨溴索辅助治疗新生儿胎粪吸入综合征(MAS)的临床疗效及对血中一氧化氮(NO)和内皮素-1(ET-1)的影响。[方法]将60例MAs患儿随机分为观察组和对照组各30例,对照组给予常规治疗,观察组在其基础上静脉滴注氨溴索;连用7d后观察两组患儿的临床疗效及血中NO、ET-1水平变化。[结果]观察组总有效率为93.33%,高于对照组的73.330.4(P〈O.05);两组患儿治疗后7d血中NO水平升高,ET-1水平降低,与治疗前比较差异有统计学意义(P〈0.05或P〈0.01),且观察组优于对照组(P〈0.05)。[结论]氨溴索治疗新生儿MAs疗效显著,可能与其调节血中NO和ET-1的水平变化有关。
作者 杨文丽
出处 《医学临床研究》 CAS 2012年第2期348-350,共3页 Journal of Clinical Research
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