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胺碘酮、贝那普利联合阿托伐他汀治疗高原阵发性心房纤颤疗效分析 被引量:4

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摘要 目的观察胺碘酮、贝那普利联合阿托伐他汀治疗高原阵发性心房纤颤的临床疗效,探讨其机制。方法将192例高原阵发性心房纤颤患者随机分为胺碘酮治疗组(A组,n=64)、胺碘酮+贝那普利(B组,n=67)和胺碘酮+贝那普利+阿托伐他汀组(C组,n=61)。随访1年,比较三组治疗前、治疗后3个月、6个月、12个月左心房内径以及窦性心律维持率。结果在维持窦性心律方面C组优于B组,B组优于A组,差异有统计学意义(P<0.05)。抑制左心房扩大方面,C组与B组优于A组,差异有统计学意义(P<0.05);C组与B组相比无统计学意义(P>0.05)。结论胺碘酮、贝那普利联合阿托伐他汀治疗高原阵发性心房纤颤的临床疗效确切,抑制炎症、逆转心房结构重构和电重构可以更有效的减少心房颤动的复发。
机构地区 解放军
出处 《西南军医》 2012年第2期266-267,共2页 Journal of Military Surgeon in Southwest China
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参考文献3

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