肾交感神经阻断术治疗难治性高血压

Renal Sympathetic Denervation for Treatment of Resistant Hypertension

交感神经的普遍激活是高血压病发病机制的重要环节,并参与难治性高血压的维持。外科交感神经切除术大大提高了难治性高血压的存活率,显示了良好的降压效果;但由于手术风险及严重术后并发症而被降压药物所代替。肾交感神经阻断术是一种新的非药物治疗方法,有损伤小、恢复快、无全身不良反应的优点,再次点燃了抑制交感神经治疗高血压病的希望。

The activation of sympathetic nerves is important in the occurrence and development of hypertension.Sympathectomy is a treatment that has increased the survival ratio of patients with resistant hypertension,resulting in significantly lowered blood pressure.However,the risks and subsequent side-effects of a sympathectomy make it necessary to use antihypertensive drugs.Renal sympathetic denervation is an alternative to sympathectomy.It is a novel nonpharmacological therapy that causes less damage,has a faster recovery time,and no severe complications.