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巨噬细胞抑制因子-1与肿瘤关系的研究进展 被引量:4

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摘要 巨噬细胞是免疫和炎症反应中一类重要的细胞,它参与许多正常的生物过程,包括损伤修复、抗肿瘤和抗感染。在类风湿性关节炎、动脉粥样硬化和肺纤维化等一系列慢性炎症、纤维变性疾病中,它也是一个重要的病理介质。巨噬细胞主要通过分泌生物活性分子,包括酶、脂类和各种细胞因子发挥作用[1]。1997年。
出处 《广东医学》 CAS CSCD 北大核心 2012年第5期702-705,共4页 Guangdong Medical Journal
基金 国家自然科学基金资助项目(编号:30973080) 广东省自然科学基金资助项目(编号:8151008901000012)
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  • 1FAIRLIE W D,MOORE A G,BAUSKIN A R,et al.MIC-1 isa novel TGF-beta superfamily cytokine associated with macro-phage activation[J].J Leukoc Biol,1999,65(1):2-5.
  • 2BOOTCOV M R,BAUSKIN A R,VALENZUELA S M,et al.MIC-1,a novel macrophage inhibitory cytokine,is a divergentmember of the TGF-beta superfamily[J].Proc Natl Acad Sci US A,1997,94(21):11514-11519.
  • 3WELSH J B,SAPINOSO L M,KERN S G,et al.Large-scaledelineation of secreted protein biomarkers overexpressed in cancertissue and serum[J].Proc Natl Acad Sci U S A,2003,100(6):3410-3415.
  • 4SCHOBER A,BOTTNER M,STRELAU J,et al.Expression ofgrowth differentiation factor-15/macrophage inhibitory cytokine-1(GDF-15/MIC-1)in the perinatal,adult,and injured ratbrain[J].J Comp Neurol,2001,439(1):32-45.
  • 5MIMEAULT M,BATRA S K.Divergent molecular mechanismsunderlying the pleiotropic functions of macrophage inhibitory cyto-kine-1 in cancer[J].J Cell Physiol,2010,224(3):626-635.
  • 6LINDMARK F,ZHENG S L,WIKLUND F,et al.H6D polymor-phism in macrophage-inhibitory cytokine-1 gene associated withprostate cancer[J].J Natl Cancer Inst,2004,96(16):1248-1254.
  • 7BROWN D A,WARD R L,BUCKHAULTS P,et al.MIC-1 ser-um level and genotype:associations with progress and prognosis ofcolorectal carcinoma[J].Clin Cancer Res,2003,9(7):2642-2650.
  • 8LEE D H,YANG Y,LEE S J,et al.Macrophage inhibitory cyto-kine-1 induces the invasiveness of gastric cancer cells by up-regulating the urokinase-type plasminogen activator system[J].Cancer Res,2003,63(15):4648-4655.
  • 9BAEK K E,YOON S R,KIM J T,et al.Upregulation and secre-tion of macrophage inhibitory cytokine-1(MIC-1)in gastriccancers[J].Clin Chim Acta,2009,401(1/2):128-133.
  • 10BOYLE G M,PEDLEY J,MARTYN A C,et al.Macrophage in-hibitory cytokine-1 is overexpressed in malignant melanoma andis associated with tumorigenicity[J].J Invest Dermatol,2009,129(2):383-391.

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