早期肠内营养支持治疗对重症脑出血病人预后和营养指标的影响

Effect of early nutrition emulsion therapy on the prognosis and nutritional indicators of patients with severe cerebral hemorrhage

目的:探讨早期肠内营养(EEN)支持治疗对急性重症脑出血病人预后和营养指标的影响。方法:将急性重症脑出血伴吞咽障碍的病人68例随机分为治疗组(n=33)和对照组(n=35),于入院后24～72 h内分别给予鼻饲EN(瑞先)支持和普通鼻饲饮食。两组病人分别于入院第2和第14天采用美国国立卫生研究院卒中量表(NIH Stroke Scale,NIHSS)进行神经功能评分,并观察营养指标的变化以及肺部感染并发症的发生率。结果:入院后第14天,治疗组病人NIHSS评分和肺部感染发生率均显著低于对照组(P<0.05),营养指标显著优于对照组。结论:EEN支持治疗可改善急性重症脑出血病人神经功能和机体的营养指标,降低感染并发症的发生率。

Objective： To investigate the early enteral nutritional emulsion（TPF） on the prognosis and nutrition indicators of patients with acute severe brain hemorrhage.Methods： 68 patients of acute severe cerebral hemorrhage accompanied with dysphagia were randomly divided into treatment group（n=33） and control group（n=35）.On 24~72 h after admission,patients in treatment group were given nasogastric enteral nutrition support with TPF while the patients in control group were treated with general nasal feeding diet.Neurological scores of patients were tested by National Institutes of Health Stroke Scale（NIH Stroke Scale,NIHSS） at 2 d and 14 d after admission respectively,and the changes of nutritional indicators and the complication of pulmonary infection were observed simultaneously.Results： At 14 d,the NIHSS and incidence of lung infection in treatment group were significantly lower than those of the control group（P0.05）,and the nutrition indicators in treatment group were also significantly improved than those of the control group.Conclusion： Early enteral nutritional support can improve the acute neurological function and nutrition indicator in patients with severe cerebral hemorrhage,and reduce the incidence of infectious complication as well.Therefore,it could be a safe and feasible way to treat the patients with severe cerebral hemorrhage.