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基于同步辐射的不同时期肿瘤新生血管形态结构定量的初步分析 被引量：3

The Preliminary Guanfifative Analysis of the Structures of Neovascular Morphology of Tumours at Different Stages Based on Syschrotron Radiation
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摘要 利用同步辐射光源显微CT造影成像获取离体乳腺癌瘤内血管网络,采用设计的分块加载双阈值分割方法提取大数据量(2GB-5GB)的瘤内血管,结合体绘制结果采用微血管密度(MICROVESSEL DENSITY,MVD)和分形维度(FRACTAL DIMENSION,FD)两个定量指标,对随时间生长的肿瘤微血管网络变化进行了初步分析。 Microvessel networks were imaged by means of synchrotron radiation CT, A sliced loading and double threshold method was utilized for extracting vessels from large quantities of data（2 GB-5 GB）. Preliminary analysis on the development of tumor microvessel networks was performed by statistically analyzing volume rendering and two qualitative factors, micro vessel density （MVD） and fractal dimension（FD）.
作者 向秋静 李晶 刘苹 孙建奇
机构地区 上海交通大学生命科学技术学院 上海交通大学生物医学工程学院和MED-X研究院
出处 《中国医疗器械杂志》 CAS 2012年第2期85-89,共5页 Chinese Journal of Medical Instrumentation
基金 国家重点基础研究发展计划(973)项目(2010CB834300) 国家自然科学基金(11005074) 上海交通大学医工(理)交叉基金(YG2010MS81)
关键词 乳腺癌 同步辐射 瘤内微血管 微血管密度(MVD) 分形维度(FD) breast cancer, synchrotron radiation, tumor microvessel, microvessel density, fractal dimension
分类号 R319 [医药卫生—基础医学]
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参考文献31

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同被引文献55

  • 1陈敏,肖体乔,骆玉宇,刘丽想,魏逊,杜国浩,徐洪杰.微聚焦管硬x射线位相衬度成像[J].物理学报,2004,53(9):2953-2957. 被引量：19
  • 2伍亚军,叶安培,王霄英,付京波,蒋学祥.基于MRI的动物肝脏脉管分割与三维重建[J].中国医学影像技术,2005,21(8):1275-1277. 被引量：2
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引证文献3

二级引证文献11

中国医疗器械杂志
2012年 第2期

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