378例社区获得性肺炎患者抗菌药物应用分析

Analysis of the Application of Antibacterial Drugs in 378 Patients with Community-acquired Pneumonia

目的:了解社区获得性肺炎(CAP)患者的抗菌药物应用情况。方法:对某院2010年7月-2011年6月378例CAP住院患者的基本资料、细菌培养及药敏试验、抗菌药物应用情况等进行回顾性分析。结果:所调查的CAP患者主要为老年患者,多有合并基础疾病,合并基础疾病种类平均为2.35种,药敏试验率为70.11%,抗菌药物种类应用例数排序列前3位的分别为氟喹诺酮类、头孢菌素类、大环内酯类。结论:该院CAP患者的临床治疗用药存在着不合理现象,需进一步采取相关措施予以改进。

OBJECTIVE：To investigate the application of antibacterial drugs in patients with community-acquired pneumonia（CAP）.METHODS：The basic information,bacterial culture,drug sensitivity test and application of antibacterial drugs in CAP patients from a hospital were analyzed retrospectively during Jul.2010-Jun.2011.RESULTS：CAP patients were mainly elderly patients,and many of them suffered from basic diseases.CAP complicating with basic disease were 2.35 averagely,and the ratio of drug sensitivity test was 70.11%.Top 3 antibacterial drugs in the list of case number were fluoroquinolones,cephalosporin and macrocyclic lactone.CONCLUSION：There exists the phenomenon of irrational drug use in CAP patients,and relevant measures should be implemented for the improvement.