摘要
目的:为心血管疾病合并糖尿病患者制订合理的药物治疗方案。方法:根据1例患者临床状况提出2个问题,通过计算机检索MEDLINE(1975年-2011年3月)、Cochrane Central Register of Controlled Trial(s2011年第1期)、Cochrane图书馆(2011年第1期),根据所获证据为患者制订药物治疗方案。结果:最终纳入3篇系统评价,14篇随机对照试验。现有证据显示:心血管疾病合并糖尿病患者的药物治疗应在避免低血糖发生的前提下使用胰岛素,并且最好使用速效人胰岛素类似物。结论:以循证医学的方法,为心血管疾病合并糖尿病患者选择合理的药物治疗方案,可降低病死率,减少不良反应的发生。
OBJECTIVE：To develop rational drug treatment plan for patients with coronary artery disease complicating with diabetes mellitus.METHODS：Two problems were put forward according to the health state of one patient.We searched MEDLINE（1975-Mar.2011）,Cochrane Central Register of Controlled Trials（No.1,2011） and Cochrane library（No.1,2011）.The drug treatment plan was made according to obtained evidence.RESULTS：3 systematic reviews and 14 RCTs were involved finally.The evidence indicated that the treatment plan of patients with coronary artery disease and diabetes mellitus should be given insulin treatment with avoiding hypoglycemia,and quick effective human insulin analog was the best.CONCLUSION：Based on evidence-based medicine,the treatment plan for patients with coronary artery disease complicating with diabetes mellitus is selected,and it reduces mortality and decreases the occurrence of adverse drug reactions.
出处
《中国药房》
CAS
CSCD
2012年第14期1330-1333,共4页
China Pharmacy
关键词
心血管疾病
糖尿病
循证药物治疗
Coronary artery disease
Diabetes mellitus
Evidence-based pharmaceutical treatment
