中老年人群肾动脉粥样硬化缺血性肾病相关因素探讨

Investigation on related factor of ischemie renal disease in middle-aged and elderly population

目的探讨中老年人群肾动脉粥样硬化缺血性肾病的相关因素,为早期诊断和早期干预创造条件。方法以2007-01～2007-12在我院进行健康体检、年龄为40～85岁的中老年人群3 000名为研究对象,通过问卷调查方式及健康体检资料进行资料搜集,调查肾动脉粥样硬化缺血性肾病患者及人群的知晓率,并分析中老年人群中发病情况、病因构成比、临床特点、治疗现况和各种独立危险因素。结果 (1)患者知晓率为3.29%,人群知晓率为0.70%。(2)患病率为5.07%,随着年龄增长,患病率明显增加;男性与女性之间患病率差异无统计学意义。(3)临床特点主要表现为高血压(83.56%)和肾功能减退(63.16%);主要合并症为冠心病(63.82%)、脑血管疾病(27.63%)、颈动脉粥样硬化(55.92%)、糖尿病(29.61%)、血脂代谢异常(53.29%)。结论肾动脉粥样硬化缺血性肾病患者及人群知晓率低;随着年龄增长,患病率明显增加;独立危险因素包括吸烟、高龄、冠状动脉病变严重程度、收缩期高血压、脑血管病、颈动脉粥样硬化、糖尿病、高低密度脂蛋白胆固醇血症等。

Objective To investigate the related factor of ischemie renal disease in middle and elderly population, to provide the possibility for early diagnosis and detection. Methods The research object included 3 000 employees and retirees （aged from 40 ~ 85 years） from the Physical Examination Center of our hospital from Jan to Dec in 2007. Their related data were colleted by using questionnaire and surveying medical examination information. （ 1 ）Investigatcd the awareness rate of the diseases, and analyzed incidence, constituent ratio on causation of disease, clinical characteristics and current therapy among them. （2） Analyzed the predicted-independent risk factors in the progression of ischemic nephropathy. R^ults （ 1 ） The awareness rate of ischemie renal disease was low： patient 3.29% ,crowd 0. 70%. （2）With the development of age, prevalence rate （5.07%） increased obviously, and the differences in prevalence rate between male and female were not statistically significant. （3）Clinical characteristics： hypertension （ 83.56% ）, renal hypofunction （ 63.16% ） ; main complication ： heart disease （ 63.81% ）, cerebrovas- cular disease （ 27. 63% ）, carotid atherosclerosis （ 55.92% ）, diabetes （ 29.60% ）, lipid dysbolism （ 53.29% ）. ConelusioR The awareness rate of ischemie renal disease is low; with the development of age, prevalence rate increased obviously ; the independent risk factors include ： smoking, advanced age, severity of coronary artery disease, systolic hypertension, cerebrovascular disease, carotid atherosclerosis, diabetes, hyper-low density lipoprotcin cholesterolemia.