长跑锻炼对老年人PBMC产生IL-2能力和对外源IL-2的反应性的影响

Ability of PBMC to Produce and Respond to IL-2 in Aged Joggers

坚持长跑锻炼10年以上的老年男性(60～72岁)安静时外周血单个核细胞产生IL-2的能力明显高于同龄对照组,对外源IL-2、PHA的反应性亦略有升高,但无统计学意义。在以25％、50％、75％PWC_(170)为强度分别运动10分钟后,其外周血单个核细胞产生IL-2的能力,对外源IL-2、PHA的反应性都有明显增高。据此认为适量的长跑锻炼对提高老年人的免疫功能是有效的。

60-72-year-old men who had participated in jogging for at least 10 years were selected to form the experiment group, Their PBMC activities of producing IL-2 and responding to IL-2, PHA at rest and during exercises of different intensities were examined and compared with those of aged men who had not had any regular physical training. At rest, the ability of PBMC to produce IL-2 in the experiment group was much greater than that of the control group, while the activities of responding to IL-2 and PHA were similar in both groups. During exercises at the intensity of 25%, 50% and 75% PWC170, the ability of PMBC to produce IL-2 and respond to IL-2,PHA were both significantly improved. Based on the results, we suggest that a moderate amount of jogging can improve the immunity of aged man.