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早期口服美托洛尔预防急性心肌梗死心律失常的临床观察

Anti arrhytlunic effect of eady treat with Metoprolol after acute myocardial infarction
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摘要 目的:探讨早期口服美托洛尔减少急性心肌梗死室性或室上性心律失常的作用。方法:将96例急性心肌梗死随机分为治疗组48例和对照组48例,治疗组在常规治疗基础上口服美托洛尔25~50mg/次,2次/d;对照组仅予常规治疗。结果:在治疗后的第3个月和第6个月时,美托洛尔组发生室性、室上性心律失常及死于心律失常的患者明显减少,与对照组相比差异具有统计学意义(P<0.05)。结论:急性心肌梗死早期口服美托洛尔能减少室性和室上性心律失常的发生。 Objective:To affirmif Metopmlol call reduce venft ricular arrhythmia and supraventrieul arrhythmia given early in acute myocardial infarction(AMI). Methods :96 patients with AMI were randomly divided into treatment group and control group, the treatment group was given Metopmlol 25 ~ 50rag, bid additionally, the control group was given conventional treatment. Results:3 and 6 months later, events of vemrieular arrhythmla, supravent- ricular arrhythmia, decease of arrhythmla in treatment group were less than those in control group (P 〈 0.05 ). Conclusion: Given early in AMI, metopmlol has a powerful ant iarr hythm ic effect in supples sing ventricular arrhythmias as w ell as supravent rieular arrhydun ias.
作者 王华 丁继军
出处 《中国民康医学》 2011年第18期2225-2225,2234,共2页 Medical Journal of Chinese People’s Health
关键词 心肌梗死 美托洛尔 心律失常 Miocardial infarction Metoprolol Arrhythmia
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参考文献5

  • 1Bangalore S,Mesaed IFH,Koafs JB,et a l.C ardiovascular p rotec-tion using betablockers:a critical revie w of the eviden ce[J].JAm Coll Cardiol,2007,50(7):563.
  • 2胡大一 马长生.心脏病学实践[M].北京:人民卫生出版社,2003.23-31.
  • 3蒋立新.静脉β受体阻滞剂在心血管急症中的应用[J].中华心血管病杂志,2004,32(9):858-861. 被引量:91
  • 4Karle CA,Kreye VA,Thomas D,et a1.Antiarrhythmie drug earve-dilol in hibits HERG potassium channels[J].Cardiovasc Res,2001,49(2):361-370.
  • 5Goldborg RJ,Yarzebski J,Lessard D,et a1.Recent trends in the in-cidence rate,of and death rates from atrial fibrillation eomplieatinginitial acute myocardial infarction:a community wide perspective[J].Am Heart J,2002,143(3):519-527.

二级参考文献16

  • 1Barron HV,Rundle AC,Gore JM,et al.Intracranial hemorrhage rates and effect of immediate beta-blocker use in patients with acute myocardial infarction treated with tissue plasminogen activator.Participants in the National Registry of Myocardial Infarction-
  • 2Harjai KJ,Stone GW,Boura J,et al.Effects of prior beta-blocker therapy on clinical outcomes after primary coronary angioplasty for acute myocardial infarction.Am J Cardiol,2003,91:655-660.
  • 3Abrams J,Allen J,Allin D,et al.Efficacy and safety of esmolol vs propranolol in the treatment of supraventricular tachyarrhythmias:a multicenter double-blind clinical trial.Am Heart J,1985,110:913-922.
  • 4Mangano DT,Goldman L.Preoperative assessment of patients with known or suspected coronary disease.N Engl J Med,1995,333:1750-1756.
  • 5Poldermans D,Boersma E,Bax JJ,et al.The effect of bisoprolol on perioperative mortality and myocardial infarction in high-risk patients undergoing vascular surgery.Dutch Echocardiographic Cardiac Risk Evaluation Applying Stress Echocardiography Study Grou
  • 6Mangano DT,Layug EL,Wallace A,et al.Effect of atenolol on mortality and cardiovascular morbidity after noncardiac surgery.Multicenter Study of Perioperative Ischemia Research Group.N Engl J Med,1996,335:1713-1720.
  • 7Ferguson TB Jr,Coombs LP,Peterson ED.Preoperative beta-blocker use and mortality and morbidity following CABG surgery in North America.JAMA,2002,287:2221-2227.
  • 8Auerbach AD,Goldman L.Beta-Blockers and reduction of cardiac events in noncardiac surgery:scientific review.JAMA,2002,287:1435-1444.
  • 9Hjalmarson A,Goldstein S,Fagerberg B,et al.Effects of controlled-release metoprolol on total mortality,hospitalizations,and well-being in patients with heart failure:the Metoprolol GR/XL.Randomized Intervention Trial in congestive heart failure(MERIT-HF).
  • 10Artman EM,Braunwald E.Acute myocardial infarction.In:Braunwald E,Zipes DP,Libby P,eds.Heart Disease:a textbook of caridovascular medicine.6th ed.Saunders:Elsevier Science,2001.1142.

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