摘要
转化生长因子β(TGF-β)是一个多功能的细胞因子,与人类许多疾病有关。TGF-β在创面修复中主要介导了细胞的迁徙、增殖、分化与凋亡,胶原、细胞外基质(ECM)的合成与降解,调节细胞与组织对损伤的反应等,被认为在创面修复过程中起了关键性的作用,影响创面修复质量。
Transforming growth factor-beta （TGF-β） is a multifunctional cytokine, which is related with many diseases. TGF-β contributes to cell migration, infiltration, proliferation, differentiation and apoptosis, extracellular matrix （ECM） and collagen formation and deposition, and regulates cell’s response to wound. TGF-β is recognized to be the key factor in wound repair and influences the quality of wound repair.
出处
《中华损伤与修复杂志（电子版）》
CAS
2011年第5期69-71,共3页
Chinese Journal of Injury Repair and Wound Healing(Electronic Edition)
基金
云南省自然科学基金资助项目(2008CD020)
关键词
转化生长因子Β
创面修复
细胞外基质
Transforming growth factor bota
Wound repair
Extracellular matrix
