综合医院住院患者合并梅毒感染的特征分析

Analysis of syphilis infection of inpatients in a comprehensive hospital

目的了解国内综合医院住院患者合并梅毒感染的现状,分析疾病流行特点,为今后的防治工作提供科学依据。方法检测梅毒感染率回顾调查一家三甲综合医院各临床科室2007-2010年住院期间患者用血清明胶凝集试验(TPPA)方法检测梅素感染率。结果本研究共调查全院住院患者180 506例,TPPA(+)患者1 236例,梅毒感染率为0.68%。平均年龄58.3岁,主要集中在50～80岁,893例,占72.25%;梅毒感染病人以初中及以下人员为主,976例,占78.96%;职业以农民和工人为主,632例,占51.13%;梅毒感染率排名前五位的科室分别是神经内科为3.00%,内分泌科为1.92%,皮肤科为1.81%,心血管内科为1.50%,呼吸科为1.43%。神经内科、内分泌科、心血管内科的住院患者中血管病变合并梅毒感染患者数比非血管病变合并梅毒感染患者数,分别是28∶9、23∶8、28∶7。结论住院患者的梅毒感染具有自己的流行特征和临床特点,本调查可为今后制定防治对策提供科学依据。

Objective To investigate status of patients with merged syphilis infection in a domestic comprehensive hospital for adults,and to provide the scientific basis for prevention and treatment in the future.Methods Retrospective survey was used to study the distribution of syphilis in patients whose serum gelatin agglutination test（TPPA） was positive in all clinical departments of a Three-grade and A-level comprehensive hospital during 2007 to 2010,and analyzed their characteristics.Results Of all 180,506 cases of hospital inpatients,1236 cases were TPPA（＋）,with syphilis infection rate of 0.68%.However,the vast majority of patients were hospitalized for non-syphilis,only 39 cases were syphilis related.The average age was 58.3 years old,mainly in 50-80 years old with 893 cases（72.2%） in all;977 cases（79%） had education below middle school;632 cases（51.2%） were in farmer and labor fields.The top five departments that had patients of syphilis infection were in Neurology（3.00%）,Endocrinology（1.92%）,Dermatology（1.81%）,Cardiology（1.50%） and Respiratory（1.43%）.Number of hospitalized patients infected with syphilis merged with vascular disease,compared with non-vascular disease syphilis infection inpatients in the department of Neurology,Endocrinology and Cardiology,were respectively 28∶9,23∶8 and 28∶7.Conclusions The prevalence of syphilis infection in hospitalized patients has its own characteristics and clinical features.Our study provides a scientific basis to draw up the countermeasures for the future.